DocumentCode
868650
Title
Modeling of skin tissue ablation by nanosecond pulses from ultraviolet to near-infrared and comparison with experimental results
Author
Fang, Qiyin ; Hu, Xin-Hua
Author_Institution
Dept. of Phys., East Carolina Univ., Greenville, NC, USA
Volume
40
Issue
1
fYear
2004
Firstpage
69
Lastpage
77
Abstract
Comprehension of biological tissue ablation by short laser pulses in a broad optical spectrum is of fundamental importance to the understanding of laser-tissue interaction and advancing surgical applications of lasers. We report a new plasma ablation model in which the chromophore ionization pathway is incorporated to explain the skin tissue ablation by nanosecond laser pulses from ultraviolet to near-infrared. A rate equation is solved to examine the effects of chromophore, cascade, and multiphoton ionization on the optical breakdown of the tissue. The wavelength and spot size dependence of the breakdown thresholds have been measured and agreements have been found between the calculated and measured results.
Keywords
biological effects of laser radiation; biological effects of ultraviolet radiation; biothermics; laser ablation; laser applications in medicine; multiphoton processes; skin; surgery; breakdown threshold; broad optical spectrum; chromophore ionization pathway; laser ablation; laser-tissue interaction; multiphoton ionization; nanosecond laser pulses; near-infrared laser pulses; optical breakdown; plasma ablation model; rate equation; skin tissue ablation; surgical applications; transient heating; ultraviolet laser pulses; Biological system modeling; Biomedical optical imaging; Electric breakdown; Ionization; Laser ablation; Laser modes; Nanobioscience; Optical pulses; Quantum cascade lasers; Skin;
fLanguage
English
Journal_Title
Quantum Electronics, IEEE Journal of
Publisher
ieee
ISSN
0018-9197
Type
jour
DOI
10.1109/JQE.2003.820837
Filename
1262088
Link To Document