Title :
Internodal myelinated segments: delay and RGC time-domain Green function model
Author :
Villapecellín-Cid, Manuel María ; Medina, Francisco ; Roa, Laura María
Author_Institution :
Escuela Superior de Ingenieria, Seville Univ., Spain
Abstract :
The myelinated axon can be modeled by means of a distributed RGC circuit. The Green function of this model allows for a generic formulation of the internodal segment response to any kind of stimulus, and accounts for the delay of the action potential associated with this segment. The RGC model accuracy is comparable to that of a more complex electromagnetic model, and predicted delay agrees with experimental measurements.
Keywords :
Green´s function methods; bioelectric potentials; inductance; neurophysiology; time-domain analysis; action potential delay; distributed RGC circuit; generic formulation; inductance; internodal myelinated segments; internodal segment response; myelinated axon; neural transmission delay; neurophysiology; simple distributed model; time domain; time-domain Green function model; Accelerometers; Cutoff frequency; Delay; Electromagnetic modeling; Frequency response; Green function; Minimization methods; Nerve fibers; Signal sampling; Time domain analysis; Action Potentials; Computer Simulation; Electric Capacitance; Electric Conductivity; Electric Impedance; Membrane Potentials; Models, Neurological; Nerve Fibers, Myelinated; Neural Conduction; Time Factors;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2003.820379
