DocumentCode :
871814
Title :
3-D Electrical Impedance Tomography for Piecewise Constant Domains With Known Internal Boundaries
Author :
Babaeizadeh, Saeed ; Brooks, Dana H. ; Isaacson, David
Author_Institution :
Adv. Algorithm Res. Center, Philips Med., Thousand Oaks, CA
Volume :
54
Issue :
1
fYear :
2007
Firstpage :
2
Lastpage :
10
Abstract :
Electrical impedance tomography (EIT) is a badly posed inverse problem, but can be stabilized if one assumes that the conductivity is piecewise constant, with a relatively small number of distinct regions, and that the region boundaries are known, for example from prior anatomical imaging. With this assumption, we introduce a three-dimensional (3-D) boundary element method (BEM) model for the forward EIT map from injected currents to measured voltages, and 3-D inverse solutions for both BEM and the finite element method (FEM) which explicitly take into account the parameterization implied by the known boundary locations. We develop expressions for the Jacobians for both methods, since they are nonlinear, to more rapidly solve the inverse problem. We show simulation results in a torso geometry with the heart and lungs as inhomogeneities. In a simulation study, we could reconstruct the conductive values of some internal organs of a human torso with more than 92% accuracy even with inaccurate internal boundary locations, a randomized rather than constant conductivity profile (with the standard deviation of the Gaussian-distributed conductivities set to 20% of their mean values), signal to measurement noise of 50 dB, and with different meshes used for the forward and inverse problems. BEM and FEM perform similarly, leading to the conclusion that the choice between them should be based on secondary considerations such as computational efficiency or the need to model conductivity anisotropies
Keywords :
Gaussian distribution; Jacobian matrices; bioelectric phenomena; boundary-elements methods; cardiology; electric impedance imaging; image reconstruction; inverse problems; lung; medical image processing; mesh generation; piecewise constant techniques; 3-d electrical impedance tomography; Gaussian-distributed conductivities; Jacobian matrix; conductivity anisotropy; conductivity reconstruction; finite element method; heart; human torso; inverse problem; known internal boundaries; lungs; mesh; piecewise constant domains; three-dimensional boundary element method; Boundary element methods; Conductivity; Current measurement; Finite element methods; Impedance; Inverse problems; Jacobian matrices; Tomography; Torso; Voltage; Boundary element methods; electrical impedance tomography; finite element methods; forward model; inverse problem; Algorithms; Computer Simulation; Diagnosis, Computer-Assisted; Electric Impedance; Heart; Humans; Imaging, Three-Dimensional; Lung; Models, Biological; Plethysmography, Impedance; Tomography;
fLanguage :
English
Journal_Title :
Biomedical Engineering, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9294
Type :
jour
DOI :
10.1109/TBME.2006.886839
Filename :
4034007
Link To Document :
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