Title :
Integrate-and-fire model for electrically stimulated nerve cell
fDate :
4/1/2006 12:00:00 AM
Abstract :
A commonly used simple spiking cell model is modified for extracellular current activation. It is proposed to simplify the simulation of a myelinated fiber nerve cell at the electrode-tissue interface by substituting for the activation site(s) identified with a more complex neuron model.
Keywords :
bioelectric phenomena; biological tissues; biomedical electrodes; cellular biophysics; neurophysiology; physiological models; complex neuron model; electrically stimulated nerve cell; electrode-tissue interface; extracellular current activation; integrate-and-fire model; myelinated fiber nerve cell; spiking cell model; Biomembranes; Cells (biology); Circuits; Displays; Electrodes; Extracellular; Mathematical model; Nerve fibers; Neurons; Switches; Computer simulation; electrical stimulation; Action Potentials; Animals; Biological Clocks; Cell Membrane; Computer Simulation; Differential Threshold; Electric Conductivity; Electric Stimulation; Humans; Models, Neurological; Neurons;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2006.870209