Title :
Building structured biomaterials using AC electrokinetics
Author :
Alp, Burçak ; Andrews, Johanna S. ; Mason, Vincent P. ; Thompson, Ian P. ; Wolowacz, Richard ; Markx, Gerard H.
Author_Institution :
Dept. of Chem. Eng., UMIST, Manchester, UK
Abstract :
In this article, the application of alternating current (ac) electrokinetics in the formation of multicellular structured biomaterials from cells is reviewed. The formation of bacterial biofilms with defined internal architectures is investigated. Investigating such interactions could not only help in understanding how biofilms operate, but biofilms could also be used as a primitive model for cell interactions and development in higher organisms such as animals and plants. A discussion on how the same techniques can be used to create multicellular systems from animal and plant cells is presented.
Keywords :
cellular transport; electric field effects; electrokinetic effects; electrophoresis; microorganisms; reviews; AC electrokinetics; animals; bacterial biofilms; cell interactions; multicellular structured biomaterials; plants; Animals; Biological materials; Buildings; Dielectrophoresis; Electric fields; Electrodes; Electrokinetics; Microorganisms; Suspensions; Temperature;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
DOI :
10.1109/MEMB.2003.1266052