DocumentCode
889844
Title
Dynamic models and solutions for evaluating ventilation, perfusion and mass transfer in the lung. I. The models
Author
Barton, Simon A. ; Black, Andrew M s ; Hahn, Clive E W
Author_Institution
Oxford Univ., UK
Volume
35
Issue
6
fYear
1988
fDate
6/1/1988 12:00:00 AM
Firstpage
450
Lastpage
457
Abstract
A dynamic model of ventilation, perfusion, and mass transfer in the lung is developed. A simple basic model is extended to permit description and prediction of dynamic performance in the presence of ventilation/perfusion (V/Q) inhomogeneity through the lung, serial deadspace, transport lags, and the dynamic effects of changing the inspired partial pressures of gases of differing solubilities (the third-gas effect). The clinical applicability of the model is discussed.
Keywords
lung; physiological models; pneumodynamics; dynamic effects; dynamic model; gas solubility; lung; mass transfer; perfusion; serial deadspace; transport lags; ventilation; ventilation/perfusion inhomogeneity; Biomedical measurements; Blood; Cardiology; Gases; Helium; Lungs; Mathematical model; Particle measurements; Predictive models; Ventilation; Lung; Mathematics; Models, Biological; Partial Pressure; Pulmonary Gas Exchange; Pulmonary Ventilation; Ventilation-Perfusion Ratio;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/10.2115
Filename
2115
Link To Document