Title :
Engineering in genomics-combinatorial optimization in biology
Author_Institution :
Sandia Nat. Lab., Albuquerque, NM
fDate :
6/1/1993 12:00:00 AM
Abstract :
The author suggests that the confidence which many biologists have in problem-solving methods is unwarranted and that there are very important limitations in almost all current methods for solving biological problems. The standard problem solving approach that computer scientists use is outlined. An example of an error in an evolutionary tree problem-the case of the African Eve-is discussed
Keywords :
combinatorial mathematics; evolution (biological); optimisation; African Eve; biologists; combinatorial optimization; computer scientists; engineering in genomics; evolutionary tree problem; problem-solving methods; Bioinformatics; Biology computing; Cities and towns; Genomics; NP-hard problem; Sequences; Software algorithms; Sorting;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
