Title :
Nanocapsules with functionalized surfaces and walls
Author :
Coelho, Manuel A N ; Gliozzi, Alessandra ; Möhwald, Helmuth ; Perez, Eric ; Sleytr, Uwe ; Vogel, Horst ; Winterhalter, Mathias
Author_Institution :
Univ. of Porto, Portugal
fDate :
3/1/2004 12:00:00 AM
Abstract :
With the possibility of creating and handling nanometer-sized objects, it became popular to dream of future miniaturized tools allowing completely new applications in medicine and technology. Mother nature created during evolution many such self-assembled highly sophisticated and robust objects, and it is very tempting to modify them for other purposes: artificial cells as intelligent submarines floating in the bloodstream attacking cancer cells, single-molecule detection and manipulation allowing the bottom-up construction of devices, and so on. Nanobiotechnology became a hot topic and significant budgets have been attributed to it. However, caution has to be paid that unrealistic dreams might have a fairly negative effect on the taxpayer seeing unkept promises. In this paper, we explore the possibilities of using biological substances in material science.
Keywords :
biochemistry; biosensors; biotechnology; cancer; drug delivery systems; enzymes; haemodynamics; molecular biophysics; nanostructured materials; polymer electrolytes; artificial cells; bloodstream; bottom-up device construction; cancer cells; functionalized surfaces; functionalized walls; intelligent submarines; molecular sensors; nanobiotechnology; nanocapsules; single-molecule detection; single-molecule manipulation; Artificial intelligence; Cancer detection; Evolution (biology); Marine technology; Nanobioscience; Nanobiotechnology; Object detection; Robustness; Self-assembly; Underwater vehicles; Biocompatible Materials; Biosensing Techniques; Capsules; Nanostructures; Nanotechnology;
Journal_Title :
NanoBioscience, IEEE Transactions on
DOI :
10.1109/TNB.2004.824277