Title :
Multifrequency Microwave-Induced Thermal Acoustic Imaging for Breast Cancer Detection
Author :
Guo, Bin ; Li, Jian ; Zmuda, Henry ; Sheplak, Mark
Author_Institution :
Univ. of Florida, Gainesville
Abstract :
Microwave-induced thermal acoustic imaging (TAI) is a promising early breast cancer detection technique, which combines the advantages of microwave stimulation and ultrasound imaging and offers a high imaging contrast, as well as high spatial resolution at the same time. A new multifrequency microwave-induced thermal acoustic imaging scheme for early breast cancer detection is proposed in this paper. Significantly more information about the human breast can be gathered using multiple frequency microwave stimulation. A multifrequency adaptive and robust technique (MART) is presented for image formation. Due to its data-adaptive nature, MART can achieve better resolution and better interference rejection capability than its data-independent counterparts, such as the delay-and-sum method. The effectiveness of this procedure is shown by several numerical examples based on 2-D breast models. The finite-difference time-domain method is used to simulate the electromagnetic field distribution, the absorbed microwave energy density, and the thermal acoustic field in the breast model.
Keywords :
biomedical ultrasonics; cancer; finite difference time-domain analysis; mammography; microwave imaging; thermoacoustics; breast model; early breast cancer detection; electromagnetic field distribution; finite-difference time-domain method; high imaging contrast; microwave stimulation; multifrequency microwave-induced thermal acoustic imaging; thermal acoustic field; ultrasound imaging; Acoustic imaging; Acoustic signal detection; Breast cancer; Cancer detection; High-resolution imaging; Humans; Microwave imaging; Microwave theory and techniques; Spatial resolution; Ultrasonic imaging; Breast cancer detection; finite-difference time-domain (FDTD) methods; multifrequency adaptive and robust technology (MART); robust capon beamforming (RCB); thermal acoustic imaging (TAI); Acoustics; Breast; Breast Neoplasms; Humans; Image Interpretation, Computer-Assisted; Microwaves; Models, Biological; Thermography;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2007.895108