Theoretical assessment of FePt nanoparticles as heating elements for magnetic hyperthermia

Author

Maenosono, Shinya ; Saita, Soichiro

Author_Institution

Dept. of Chem. Syst. Eng., Univ. of Tokyo

Volume

42

Issue

6

fYear

2006

fDate

6/1/2006 12:00:00 AM

Firstpage

1638

Lastpage

1642

Abstract

FePt magnetic nanoparticles (MNPs) are expected to be a high-performance nanoheater for magnetic hyperthermia because of their high Curie temperature, high saturation magnetization, and high chemical stability. Here, we present a theoretical performance assessment of chemically disordered fcc-phase FePt MNPs. We calculate heat generation and heat transfer in the tissue when an MNP-loaded tumor is placed on an external alternating magnetic field. For comparison, we estimate the performances of magnetite, maghemite, FeCo, and L1₀-phase FePt MNPs. We find that an fcc FePt MNP has a superior ability in magnetic hyperthermia

Keywords

biothermics; cancer; heat transfer; hyperthermia; iron alloys; magnetic particles; nanoparticles; platinum alloys; tumours; FePt; bioheat transfer equation; cancer treatment; magnetic hyperthermia; magnetic nanoparticles; Chemical elements; Heat transfer; Heating; Hyperthermia; Magnetic fields; Nanoparticles; Neoplasms; Saturation magnetization; Stability; Temperature; Bioheat transfer equation; cancer treatment; hyperthermia; iron-platinum nanoparticle;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/TMAG.2006.872198

Filename

1634472