Title :
Rapid Extension of Single and Double Stranded DNA on Atomically Flat Conductive Surfaces
Author :
Mehta, Ranjana ; Rahimi, Maryam ; Lund, John A. ; Parviz, Babak A.
Author_Institution :
Univ. of Washington, Seattle
Abstract :
We report a simple method for extending DNA on atomically flat conductive graphite and gold surfaces employing molecular combing and using either coordinating ions on graphite or self-assembled molecular monolayers on gold. Extended DNA molecules on conductive surfaces can be used as platforms for building nanoscale electronic devices or used for direct electronic sequencing.
Keywords :
DNA; genetics; gold; graphite; molecular biophysics; monolayers; nanobiotechnology; self-assembly; Au - Surface; C - Surface; atomically flat conductive surfaces; conductive graphite surface; coordinating ions; direct electronic sequencing; double stranded DNA; gold surfaces; molecular combing; nanoscale electronic devices; rapid DNA extension; self-assembled molecular monolayers; single stranded DNA; DNA extension; DNA nanostructures; Electronic DNA sequencing; Molecular combing; electronic DNA sequencing; molecular combing;
Journal_Title :
Nanotechnology, IEEE Transactions on
DOI :
10.1109/TNANO.2007.908169
