DocumentCode
955019
Title
Measuring and Extraction of Biological Information on New Handheld Biochip-Based Microsystem
Author
Lopes, Paulo A C ; Germano, José ; De Almeida, Teresa Mendes ; Sousa, Leonel Augusto ; Piedade, Moisés S. ; Cardoso, Filipe Arroyo ; Ferreira, H.A. ; Freitas, Paulo P.
Author_Institution
Inst. Super. Tecnico, Tech. Univ. of Lisbon, Lisbon, Portugal
Volume
59
Issue
1
fYear
2010
Firstpage
56
Lastpage
62
Abstract
This paper proposes techniques for the extraction of biological information in a recently developed handheld biochip-based microsystem. The microsystem is based on a magnetoresistive array biochip composed of a number of sensing sites with magnetic tunneling junctions (MTJ) and diodes. Different techniques are addressed to drive the MTJs with different types of signals. Different filtering strategies that allow the recovery of biological signals from the noise without overly increasing either the time required for accessing the sensors or the power consumption of the board are proposed. Finally, new techniques and algorithms are proposed to deal with the variability of the fabrication parameters of the MTJ and the diodes. Experiments with the system in a setup to detect actual biological signals are presented with encouraging results.
Keywords
bioMEMS; biological techniques; biology computing; biomagnetism; filtering theory; lab-on-a-chip; magnetic sensors; magnetic tunnelling; magnetoresistive devices; signal processing; biological information extraction; biological signal; filtering strategy; handheld biochip-based microsystem; magnetic sensors; magnetic tunneling junction; magnetoresistive array biochip; signal processing; Biochip; biomolecules; magnetic sensors; microsystem; signal processing;
fLanguage
English
Journal_Title
Instrumentation and Measurement, IEEE Transactions on
Publisher
ieee
ISSN
0018-9456
Type
jour
DOI
10.1109/TIM.2008.2003321
Filename
4652562
Link To Document