DocumentCode :
955019
Title :
Measuring and Extraction of Biological Information on New Handheld Biochip-Based Microsystem
Author :
Lopes, Paulo A C ; Germano, José ; De Almeida, Teresa Mendes ; Sousa, Leonel Augusto ; Piedade, Moisés S. ; Cardoso, Filipe Arroyo ; Ferreira, H.A. ; Freitas, Paulo P.
Author_Institution :
Inst. Super. Tecnico, Tech. Univ. of Lisbon, Lisbon, Portugal
Volume :
59
Issue :
1
fYear :
2010
Firstpage :
56
Lastpage :
62
Abstract :
This paper proposes techniques for the extraction of biological information in a recently developed handheld biochip-based microsystem. The microsystem is based on a magnetoresistive array biochip composed of a number of sensing sites with magnetic tunneling junctions (MTJ) and diodes. Different techniques are addressed to drive the MTJs with different types of signals. Different filtering strategies that allow the recovery of biological signals from the noise without overly increasing either the time required for accessing the sensors or the power consumption of the board are proposed. Finally, new techniques and algorithms are proposed to deal with the variability of the fabrication parameters of the MTJ and the diodes. Experiments with the system in a setup to detect actual biological signals are presented with encouraging results.
Keywords :
bioMEMS; biological techniques; biology computing; biomagnetism; filtering theory; lab-on-a-chip; magnetic sensors; magnetic tunnelling; magnetoresistive devices; signal processing; biological information extraction; biological signal; filtering strategy; handheld biochip-based microsystem; magnetic sensors; magnetic tunneling junction; magnetoresistive array biochip; signal processing; Biochip; biomolecules; magnetic sensors; microsystem; signal processing;
fLanguage :
English
Journal_Title :
Instrumentation and Measurement, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9456
Type :
jour
DOI :
10.1109/TIM.2008.2003321
Filename :
4652562
Link To Document :
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