• DocumentCode
    955019
  • Title

    Measuring and Extraction of Biological Information on New Handheld Biochip-Based Microsystem

  • Author

    Lopes, Paulo A C ; Germano, José ; De Almeida, Teresa Mendes ; Sousa, Leonel Augusto ; Piedade, Moisés S. ; Cardoso, Filipe Arroyo ; Ferreira, H.A. ; Freitas, Paulo P.

  • Author_Institution
    Inst. Super. Tecnico, Tech. Univ. of Lisbon, Lisbon, Portugal
  • Volume
    59
  • Issue
    1
  • fYear
    2010
  • Firstpage
    56
  • Lastpage
    62
  • Abstract
    This paper proposes techniques for the extraction of biological information in a recently developed handheld biochip-based microsystem. The microsystem is based on a magnetoresistive array biochip composed of a number of sensing sites with magnetic tunneling junctions (MTJ) and diodes. Different techniques are addressed to drive the MTJs with different types of signals. Different filtering strategies that allow the recovery of biological signals from the noise without overly increasing either the time required for accessing the sensors or the power consumption of the board are proposed. Finally, new techniques and algorithms are proposed to deal with the variability of the fabrication parameters of the MTJ and the diodes. Experiments with the system in a setup to detect actual biological signals are presented with encouraging results.
  • Keywords
    bioMEMS; biological techniques; biology computing; biomagnetism; filtering theory; lab-on-a-chip; magnetic sensors; magnetic tunnelling; magnetoresistive devices; signal processing; biological information extraction; biological signal; filtering strategy; handheld biochip-based microsystem; magnetic sensors; magnetic tunneling junction; magnetoresistive array biochip; signal processing; Biochip; biomolecules; magnetic sensors; microsystem; signal processing;
  • fLanguage
    English
  • Journal_Title
    Instrumentation and Measurement, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9456
  • Type

    jour

  • DOI
    10.1109/TIM.2008.2003321
  • Filename
    4652562