DocumentCode :
960710
Title :
Scalar equations for synchronous Boolean networks with biological applications
Author :
Farrow, Christopher ; Heidel, Jack ; Maloney, John ; Rogers, Jim
Author_Institution :
Dept. of Math., Univ. of Nebraska, Omaha, NE, USA
Volume :
15
Issue :
2
fYear :
2004
fDate :
3/1/2004 12:00:00 AM
Firstpage :
348
Lastpage :
354
Abstract :
One way of coping with the complexity of biological systems is to use the simplest possible models which are able to reproduce at least some nontrivial features of reality. Although two value Boolean models have a long history in technology, it is perhaps a little bit surprising that they can also represent important features of living organizms. In this paper, the scalar equation approach to Boolean network models is further developed and then applied to two interesting biological models. In particular, a linear reduced scalar equation is derived from a more rudimentary nonlinear scalar equation. This simpler, but higher order, two term equation gives immediate information about both cycle and transient structure of the network.
Keywords :
Boolean functions; biology; nonlinear equations; synchronisation; biological applications; linear reduced scalar equation; nonlinear scalar equation; synchronous Boolean network; Algebra; Biological system modeling; Biological systems; History; Large-scale systems; Lifting equipment; Mathematics; Nonlinear equations; Physics; Proteins; Computational Biology; Neural Networks (Computer);
fLanguage :
English
Journal_Title :
Neural Networks, IEEE Transactions on
Publisher :
ieee
ISSN :
1045-9227
Type :
jour
DOI :
10.1109/TNN.2004.824262
Filename :
1288239
Link To Document :
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