Title :
The Influence of Porous Silicon on Axonal Outgrowth in Vitro
Author :
Johansson, Fredrik ; Kanje, Martin ; Linsmeier, Cecilia Eriksson ; Wallman, Lars
Author_Institution :
Lund Univ., Lund
fDate :
4/1/2008 12:00:00 AM
Abstract :
Axonal outgrowth on smooth and porous silicon surfaces was studied in organ culture. The pore size of the silicon substrata varied between 100 and 1500 nm. We found that axons preferred to grow and elongate on porous silicon surfaces only when pores of (150-500 nm) are available.
Keywords :
biomechanics; cellular biophysics; elemental semiconductors; nanobiotechnology; nanoporous materials; neurophysiology; silicon; axonal outgrowth in vitro; organ culture; pore size; porous silicon surfaces; silicon substrate; Adhesives; Animals; Biomedical imaging; Cells (biology); Hafnium; In vitro; Nerve fibers; Organisms; Permission; Scanning electron microscopy; Silicon; Axon; Porous silicon; axonal outgrowth; guidance; haptotaxis; pore size; porous silicon; Animals; Axons; Biocompatible Materials; Cell Enlargement; Cells, Cultured; Female; Ganglia, Spinal; Materials Testing; Mice; Porosity; Posterior Horn Cells; Silicon;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2007.912423
