Title :
Performance evaluation of the fully engineered YAP-(S)PET scanner for small animal imaging
Author :
Del Guerra, Alberto ; Bartoli, Antonietta ; Belcari, Nicola ; Herbert, Deborah ; Motta, Alfonso ; Vaiano, Angela ; Domenico, Giovanni Di ; Sabba, Nicola ; Moretti, Elena ; Zavattini, Guido ; Lazzarotti, Marco ; Sensi, Luca ; Larobina, Michele ; Uccelli, L
Author_Institution :
Dept. of Phys. & Center of Excellence AmbiSEN, Univ. of Pisa, Italy
fDate :
6/1/2006 12:00:00 AM
Abstract :
At the Department of Physics of the University of Pisa, Italy, a new and fully engineered version of the YAP-(S)PET small animal scanner has been recently installed. The new YAP-(S)PET is able to perform both PET and SPECT studies on small animals. The scanner is made up of four heads: each one is composed of a 4×4 cm2 YAlO3:Ce (or YAP:Ce) matrix of 20×20 elements, 2×2×25 mm3 each, coupled to a Position Sensitive Photomultiplier (PS-PMT) (Hamamatsu R2486). The four modules are positioned on a rotating gantry. The switching to the SPECT modality is easily made by mounting a high resolution parallel hole (0.6 mm O, 0.15 mm septum) lead collimator in front of each crystal. This paper reports the performance of the system in terms of absolute sensitivity and spatial resolution for both PET and SPECT modalities. The scatter fraction and noise-equivalent count rate (NEC) for a mouse phantom for different energy windows have been measured in PET modality. Images of phantoms and animals are also presented.
Keywords :
image scanners; phantoms; photomultipliers; position sensitive particle detectors; positron emission tomography; single photon emission computed tomography; solid scintillation detectors; PET modality; SPECT modality; YAlO3:Ce matrix; absolute sensitivity; fully engineered YAP-(S)PET scanner; high resolution parallel hole lead collimator; molecular imaging; mouse phantom image; noise-equivalent count rate; position sensitive photomultiplier; positron emission tomography; rotating gantry; scatter fraction; single photon emission tomography; small animal imaging; Animals; Collimators; Head; Imaging phantoms; National electric code; Photomultipliers; Physics; Positron emission tomography; Scattering; Spatial resolution; Molecular imaging; positron emission tomography (PET); single photon emission tomography; small animal imaging;
Journal_Title :
Nuclear Science, IEEE Transactions on
DOI :
10.1109/TNS.2006.871900