Title :
Effect of randoms on signal-to-noise ratio in TOF PET
Author_Institution :
Siemens Med. Solution, Molecular Imaging, Knoxville, TN, USA
fDate :
6/1/2006 12:00:00 AM
Abstract :
Time-of-flight (TOF) positron emission tomography (PET) has the potential to improve signal-to-noise ratio (SNR). In the literature, this improvement has been estimated as proportional to the square root of D/Δx, where D is the radial dimension of the object to be imaged, and Δx is the spatial uncertainty associated with the time resolution of the scanner. This estimate does not include the effect of the randoms. In this paper we discuss the role of random coincidence in TOF PET; in particular, the improvement in SNR due to random reduction in TOF PET. We introduce and discuss a simple model for this improvement, modify the traditional estimate for SNR gain, and compare it to experimental data from a Siemens Hi-Rez PET scanner with TOF capability.
Keywords :
positron emission tomography; solid scintillation detectors; LSO detector; SNR gain; Siemens Hi-Rez PET scanner; TOF PET; object radial dimension; random coincidence; random reduction; scanner time resolution; signal-to-noise ratio; spatial uncertainty; time-of-flight positron emission tomography; Detectors; Image resolution; Lanthanum; National electric code; Photonic crystals; Positron emission tomography; Signal resolution; Signal to noise ratio; Spatial resolution; Time measurement; PET; TOF; randoms; signal-to-noise ratio; time-of-flight;
Journal_Title :
Nuclear Science, IEEE Transactions on
DOI :
10.1109/TNS.2006.875066
