• DocumentCode
    998819
  • Title

    Ultra-sensitive immunoassay using VCSEL detection system

  • Author

    Mateus, C.F.R. ; Huang, M.C.Y. ; Chang-Hasnain, C.J. ; Foley, J.E. ; Beatty, R. ; Li, P. ; Cunningham, Brian T.

  • Author_Institution
    Electr. Eng. & Comput. Sci. Dept., Univ. of California, Berkeley, CA, USA
  • Volume
    40
  • Issue
    11
  • fYear
    2004
  • fDate
    5/27/2004 12:00:00 AM
  • Firstpage
    649
  • Lastpage
    651
  • Abstract
    Highly sensitive protein characterisation on a new label-free biosensor system is reported. The system consists of a VCSEL, a plastic guided mode resonant filter and two pin detectors. It is suitable for measuring both static and dynamic interaction among proteins and can detect an antigen concentration as low as 1 pg/ml (6.7 femtoMolar).
  • Keywords
    biosensors; molecular biophysics; proteins; resonator filters; surface emitting lasers; VCSEL detection system; antigen concentration; dynamic interaction; label free biosensor system; pin detectors; plastic guided mode resonant filter; protein characterisation; proteins; static interaction; ultra sensitive immunoassay; vertical cavity surface emitting layer;
  • fLanguage
    English
  • Journal_Title
    Electronics Letters
  • Publisher
    iet
  • ISSN
    0013-5194
  • Type

    jour

  • DOI
    10.1049/el:20040491
  • Filename
    1302781
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=998819