آپانديسيت حاد شايعترين بيماري حاد جراحي است و هدف از اين مطالعه بررسي فراواني و ارزش تشخيصي علائم، نشانهها و يافتههاي پاراكلينيك در بيماران مشكوك به آپانديسيت حاد در پيشبيني وجود يا عدم وجود آپانديسيت حاد بوده است. در اين مطالعه 1211 بيمار مشكوك به آپانديسيت حاد كه تحت عمل آپاندكتومي قرار گرفته بودند، در مدت 2 سال بررسي شدند. در تجزيه و تحليل نتايج از تست One way ANOVA، ضريبهاي هم بستگي Kappa، نسبت شانس(Odds ratio) و مدل رگرسيوني لجستيك(براي پيشبيني وجود آپانديسيت) استفاده شد. ميزان آپاندكتومي منفي در اين مطالعه 2/18% بود كه با توجه به متفاوت بودن جراحان بين 4 تا 7/27% به دست آمد(0/001=P). مدل رگرسيوني نشان داد كه سن بالاتر(0/005=P)، جنسيت مرد(0/002=P)، ميزان بالاتر (PMN(P=0/027 و تعداد بيشتر ضربان قلب(0/014=P) از ميان متغيرهايي كه تفاوت معنيداري بين افراد با آپاندكتومي منفي و افراد ديگر داشتند، متغيرهايي هستند كه ميتوانند به طور مستقل، وجود آپانديسيت حاد را پيشبيني كنند(0/001
چكيده لاتين :
Acute appendicitis is still the most common acute surgical disease. The aim of this study was to
evaluate the frequency of symptoms, signs, paraclinical findings and diagnostic value of these
findings in prediction of acute appendicitis in patients suspicious of having this problem. In this study
1121 patients, suspicious of acute appendicitis, were operated and surveyed in the period of two
years. One way ANOVA, kappa and odds ratio correlation coefficient and logistic regression model
were used to analyse the data and to predict the occurrence of acute appendicitis. 92.4% of the
patients were males, and the average age was 24.1 years. The rate of negative appendectomy in
this study was 18.2%, which ranged between 4% and 27.7% based on diagnosis made by various
physicians(P=0.001). The regression model revealed that among factors which showed significant
difference between negative appendectomy patients and the rest, only older age(P=0.005), male
gender(P=0.002), higher percenage of PMN(P=0.027) and higher heart rate(P=0.014) could be
regarded as independent predictors of acute appendicitis(P<0.001). In conclusion, based on the
results of this study, it is reasonable to be hesitant about operating a female patient suspicious of
having acute appendicitis, if she has a PMN percentage of lower than 75%, white cells less than
10,000 in milliliter, urinary symptoms and no rebound tenderness or questionable rebound
tenderness.