مقايسه خاصيت ضدميكروبي محلول ايراني سيلوسپت با بتادين براي اسكراب دست قبل از عمل و مطلوبيت آن از نظر تيم جراحي به عنوان جايگزين

Antimicrobial activity of Iranian "SilvoSept" compared with povidone iodine for hand scrub before surgery and its utility as an alternative solution from the perspective of the surgical team

ﺳﺎﺑﻘﻪ و ﻫﺪف: ﺳﯿﻠﻮﺳﭙﺖ" ﻣﺤﺼﻮل ﺟﺪﯾﺪي اﺳﺖ ﮐﻪ ﺑﻪ ﺟﺎي ﺑﺘﺎدﯾﻦ ﺑﺮاي اﺳﮑﺮاب دﺳﺖ ﻫﺎ ﻗﺒﻞ از اﻧﺠـﺎم ﻋﻤـﻞ ﺟﺮاﺣﯽ ﭘﯿﺸﻨﻬﺎد ﺷﺪه اﺳﺖ. ﻫﺪف از اﯾﻦ ﻣﻄﺎﻟﻌﻪ، ﻣﻘﺎﯾﺴﻪ دو ﻣﺎده از ﻧﻈﺮ ﺧﻮاص آﻧﺘﯽ ﺳﭙﺘﯿﮏ و ﻣﻘﺒﻮﻟﯿﺖ ﺑﻮد. ﻣﻮاد و روش ﻫﺎ: در ﯾﮏ ﻣﻄﺎﻟﻌﻪ ﺷﺒﻪ ﺗﺠﺮﺑﯽ، اﻋﻀﺎي ﺗﯿﻢ ﺟﺮاﺣﯽ ﺑﯿﻤﺎرﺳﺘﺎن اﻣﯿﺮ اﻟﻤـﻮﻣﻨﯿﻦ ﺳـﻤﻨﺎن در دو ﻧﻮﺑـﺖ ﺑـﺎ ﺳﯿﻠﻮﺳﭙﺖ و ﺑﺘﺎدﯾﻦ اﻗﺪام ﺑﻪ اﺳﮑﺮاب دﺳﺖ ﻧﻤﻮدﻧﺪ. از ﻧﻤﻮﻧﻪ دﺳﺖ ﻏﺎﻟﺐ، ﻗﺒﻞ، ﺑﻌﺪ از ﺧﺸﮏ ﺷﺪن و 1 ﺳـﺎﻋﺖ ﺑﻌـﺪ از ﺷﺴﺘﺸﻮ ﮐﺸﺖ ﻣﯿﮑﺮوﺑﯽ ﺑﻪ ﻋﻤﻞ آﻣﺪ و ﻣﻄﻠﻮﺑﯿﺖ ﻫﺮ ﻣﺎده ﻧﯿﺰ از اﯾﺸﺎن ﺳﻮال ﺷﺪ. ﯾﺎﻓﺘﻪ ﻫﺎ: 33 ﺷﺮﮐﺖ ﮐﻨﻨﺪه، 29 ﺑﺎر ﺑﺎ ﺳﯿﻠﻮﺳﭙﺖ و 33 ﺑﺎر ﺑﺎ ﺑﺘﺎدﯾﻦ اﺳﮑﺮاب ﻧﻤﻮدﻧﺪ. ﺗﻔـﺎوﺗﯽ از ﻧﻈـﺮ ﻣﺜﺒـﺖ ﺷـﺪن ﮐﺸﺖ ﻗﺒﻞ از ﺷﺴﺘﺸﻮ (0/7=p) و ﯾﮏ ﺳﺎﻋﺖ ﺑﻌﺪ (0/5=p) ﮔﺰارش ﻧﺸﺪ. ﺑﻼﻓﺎﺻﻠﻪ ﺑﻌﺪ از ﺷﺴﺘﺸﻮ ﻧﯿﺰ اﺻﻼً ﻣﻮرد ﻣﺜﺒﺘﯽ وﺟﻮد ﻧﺪاﺷﺖ. ﮔﺮﭼﻪ ﺗﻔﺎوﺗﯽ ﻣﯿﺎن دو ﻣﺎده از ﻧﻈﺮ ﺗﻤﺎﯾﻞ اﻓﺮاد (0/7=p) و ﺑﺪ ﺑﻮﯾﯽ (0/3=p) دﯾﺪه ﻧﺸﺪ، اﻣﺎ از ﻧﻈـﺮ ﺗـﺎﺛﯿﺮ ﻧﺎﻣﻄﻠﻮب ﺑﺮ ﭘﻮﺳﺖ (0/04=p)و ﺑﺪ رﻧﮕﯽ (0/03=p) ﺷﺮﮐﺖ ﮐﻨﻨﺪﮔﺎن ﺳﯿﻠﻮﺳﭙﺖ را ﺑﻬﺘﺮ داﻧﺴﺘﻨﺪ. ﻧﺘﯿﺠﻪ ﮔﯿﺮي: ﯾﺎﻓﺘﻪ ﻫـﺎ ﺿـﻤﻦ ﺗﺎﯾﯿـﺪ ﺑﺮاﺑـﺮي دو ﻣـﺎده از ﻧﻈـﺮ ﺗـﺎﺛﯿﺮ ﺿـﺪ ﻣﯿﮑﺮوﺑـﯽ و ﺗﻤﺎﯾـﻞ اﻓـﺮاد، ﻧﺸـﺎن داد اﺳﺘﻔﺎده ﮐﻨﻨﺪﮔﺎن ﺑﻪ دﻟﯿﻞ ﺑﺪ رﻧﮕﯽ و ﻋﻮارض ﻧﺎﻣﻄﻠﻮب ﭘﻮﺳﺘﯽ، ﺳﯿﻠﻮﺳﭙﺖ را ﺑﺮ ﺑﺘﺎدﯾﻦ ﺗﺮﺟﯿﺢ ﻣﯽ دﻫﻨﺪ. ﺳﯿﻠﻮﺳـﭙﺖ ﺑـﻪ ﻋﻨﻮان ﺟﺎي ﮔﺰﯾﻨﯽ ﻣﻮﺛﺮ، ﻣﻘﺒﻮل و ﻣﻘﺮون ﺑﻪ ﺻﺮﻓﻪ ﻗﺎﺑﻞ ﭘﯿﺸﻨﻬﺎد اﺳﺖ.

Introduction: "SilvoSept" is a new product, suggested as an alternative solution instead of povidone iodine for hand scrub before surgery. The objective of study was the comparison between these two substances regarding their antiseptic properties and utilities. Materials and Methods: In a quasi-experimental study, selected participants from surgical team members of Amir Hospital in Semnan were participated to scrub their hands with SilvoSept and povidone iodine, in two separate times. Dominant hand was sampled 3 times to get microbial cultures: before scrubbing, after drying, and after an hour. Participants were asked about each solution's utilities. Results: Thirty-three participants scrubbed for 29 and 33 times with povidone iodine and SilvoSept respectively. There was no difference between two groups in positive culture frequencies before washing (p = 0.7), and an hour later (p = 0.5). Immediately after washing, there was no positive case. Although there was no difference between the two in terms of willingness (p = 0.7) and bad odor (p = 0.3), due to having adverse impact on the skin (p = 0.04) and bad color (p = 0.03) participants preferred SilvoSept. Conclusion: The findings not only confirmed the antimicrobial effectiveness of the SilvoSept, and its equality with povidone iodine on willingness of applying, but also showed its superiority to povidone iodine because of its lower adverse effects on skin as well as its better color. SilvoSept can be suggested as an effective, acceptable and affordable alternative.