بررسي تاثير كتامين خوراكي به عنوان پيش داروي بيهوشي بر آمادگي كودكان جهت عمل جراحي

A Study on Oral Ketamine premedication Effects on Preparation of Children for Surgery

This is a semi-experimental and double blind study which was performed on 66 children of 2-7 years of age who had been referred for the first time, for non-brain and non-liver elective surgery (class 1 anesthesia). This study was designed to define the efficacy of oral ketamine on agitation and crying of children after separation from their parents, toleration of anesthesia mask and I.V needle, sleeping before anesthesia and entry into the operating room. Samples were divided into two groups, case and control. 5mg/kg of ketamine plus 0.2cc/kg of fruit juice was given to the case group while only 0.2cc/kg of fruit juice was given to the control group 30 minutes before the operation. Our results showed that 78.8% of children in the case group did not cry when they were separated from their parents and 78.7% of them did not show any resistance. 34.4% of children in the case group showed no response to insertion of an I.V needle and 59.4% of them showed minor responses. 6.1% of children in the control group had no response while 78.7% of them had responses such as intense body movements and pulling of hands. 69.7% of the case group were cooperative when putting on the anesthesia mask while 75.8% of the control group refused to wear the mask. 81.8% of the children in the case group were asleep before anesthesia while all of the children in the control group were awake and uneasy.These findings indicate that ketamine can be used as a preanesthetic drug to decrease the anxiety and fear of children and to calm them before their transfer to the operating room.