ﺑﺮرﺳﯽ ارﺗﺒﺎط ﺑﯿﻦ ﺟﻨﺴﯿﺖ، ﺳﻦ و ﻣﺤﻞ زﻧﺪﮔﯽ ﺑﺎ ﺷﯿﻮع ﺑﯿﻤﺎري ﮐﻮﻟﻪﺳﯿﺴﺘﯿﺖ ﺣﺎد و ﻣﺰﻣﻦ و ﮐﺎرﺳﯿﻨﻮم ﮐﯿﺴﻪ ﺻﻔﺮا در ﺑﯿﻤﺎران ﮐﻮﻟﻪﺳﯿﺴﺘﮑﺘﻮﻣﯽ ﺷﺪه در ﺑﯿﻤﺎرﺳﺘﺎن اﻣﯿﺮاﻟﻤﻮﻣﻨﯿﻦ زاﺑﻞ در ﺳﺎل 1394

Investigation of Relationship between Gender, Age and Living Place with Outbreak of Acute and Chronic Cholecystetomy and Gall Bladder Carcinoma in Amiralmomenin Hospital of Zabol in 1394

زﻣﯿﻨﻪ و ﻫﺪف: ﮐﻮﻟﻪ ﺳﯿﺴﺘﯿﺖ ﺑﻪ اﻟﺘﻬﺎب ﮐﯿﺴﻪ ﺻﻔﺮا ﮔﻔﺘﻪ ﻣﯽﺷﻮد ﮐﻪ اﻏﻠﺐ ﺑﻪ دﻟﯿﻞ اﻧﺴﺪاد ﻣﺠﺮاي ﺳﯿﺴﺘﯿﮏ ﺑﻪ وﺳﯿﻠﻪ ﺳﻨﮓ اﯾﺠﺎد ﻣﯽﺷﻮد. ﺑﯿﻤﺎريﻫﺎي ﮐﯿﺴﻪ ﺻﻔﺮا ﺑﻪ ﺻﻮرت ﺳﻨﮓﻫﺎي ﺻﻔﺮاوي ﯾﺎ ﮐﺎرﺳﯿﻨﻮم ﮐﯿﺴﻪ ﺻﻔﺮا ﺗﻈﺎﻫﺮ ﭘﯿﺪا ﻣﯽﮐﻨﻨﺪ و 10 ﺗﺎ 15 درﺻﺪ از ﺟﻤﻌﯿﺖ ﺑﺰرﮔﺴﺎﻻن را ﺗﺤﺖ ﺗﺄﺛﯿﺮ ﺧﻮد ﻗﺮار ﻣﯽدﻫﻨﺪ. ﻫﺪف از اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﺑﺮرﺳﯽ ﺷﯿﻮع ﮐﻠﻪ ﺳﯿﺴﺘﯿﺖ ﺑﻪ ﺻﻮرت ﺣﺎد، ﻣﺰﻣﻦ و ﮐﺎرﺳﯿﻨﻮم ﮐﯿﺴﻪ ﺻﻔﺮا در اﻓﺮاد ﻣﺒﺘﻼ ﮐﻪ ﺗﺤﺖ ﻋﻤﻞ ﺟﺮاﺣﯽ ﻗﺮار ﮔﺮﻓﺘﻨﺪ، ﻣﯽﺑﺎﺷﺪ. ﻣﻮاد و روش ﻫﺎ: اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﺑﺮ روي ﺑﯿﻤﺎراﻧﯽ ﮐﻪ در ﻃﻮل ﺳﺎل 1394 در ﺑﯿﻤﺎرﺳﺘﺎن اﻣﯿﺮاﻟﻤﻮﻣﻨﯿﻦ زاﺑﻞ ﺑﺎ ﺗﺸﺨﯿﺺ ﮐﻠﻪ ﺳﯿﺴﺘﯿﺖ ﺑﺴﺘﺮي و ﺗﺤﺖ ﻋﻤﻞ ﺟﺮاﺣﯽ ﻗﺮار ﮔﺮﻓﺘﻪ ﺑﻮدﻧﺪ، اﻧﺠﺎم ﮔﺮﻓﺖ. ﺗﻘﺴﯿﻢﺑﻨﺪي ﺑﯿﻤﺎران در ﺳﻪ ﮔﺮوه ﮐﻠﻪ ﺳﯿﺴﺘﯿﺖ ﺣﺎد و ﻣﺰﻣﻦ و ﮐﺎرﺳﯿﻨﻮم ﮐﯿﺴﻪ ﺻﻔﺮا ﺑﺮ اﺳﺎس ﯾﺎﻓﺘﻪﻫﺎي ﺟﺮاﺣﯽ و ﭘﺎﺗﻮﻟﻮژي ﺑﯿﻤﺎر ﺑﺮاﺳﺎس ﺳﻦ، ﺟﻨﺲ و ﻣﺤﻞ زﻧﺪﮔﯽ اﻓﺮاد اﻧﺠﺎم ﮔﺮﻓﺖ و دادهﻫﺎ ﺗﻮﺳﻂ آزﻣﻮن ﻣﺠﺬور ﮐﺎي و ﺑﺎ اﺳﺘﻔﺎده از ﻧﺮم اﻓﺰار 21 SPSS ﺗﺠﺰﯾﻪ و ﺗﺤﻠﯿﻞ ﮔﺮدﯾﺪ. ﯾﺎﻓﺘﻪ ﻫﺎ: از 271 ﺑﯿﻤـﺎر ﺑﺮرﺳـﯽ ﺷـﺪه در اﯾﻦ ﻣﻄﺎﻟﻌﻪ 199 )73/44 درﺻﺪ( ﻣـﻮرد زن و 72 )26/56 درﺻﺪ( ﻣـﻮرد ﻣـﺮد، 131 )48/3 درﺻﺪ( ﻧﻔﺮ روﺳﺘﺎﯾﯽ و 140 )51/7 درﺻﺪ( ﻧﻔﺮ ﺷﻬﺮﻧﺸﯿﻦ ﺑﻮدﻧﺪ. 39 )51/3 درﺻﺪ( ﻣﻮرد ﮐﻠﻪ ﺳﯿﺴﺘﯿﺖ ﻣﺰﻣﻦ، 124 )45/8 درﺻﺪ( ﻣـﻮرد ﮐﻠﻪ ﺳﯿﺴﺘﯿﺖ ﺣـﺎد و 8 )3 درﺻﺪ( ﻣﻮرد ﻣﺒﺘﻼ ﺑﻪ ﮐﺎرﺳﯿﻨﻮم ﮐﯿﺴﻪ ﺻﻔﺮا ﺑﻮدﻧﺪ. ﺑﺎﻻﺗﺮﯾﻦ ﻣﯿﺰان ﺷﯿﻮع ﮐﻠﻪ ﺳﯿﺴﺘﯿﺖ در ﺳﻨﯿﻦ ﺑﯿﻦ 40 ﺗﺎ50 ﺳﺎﻟﮕﯽ )24/7%( ﻣﺸﺎﻫﺪه ﺷﺪ. ﻧﺘﯿﺠﻪ ﮔﯿـﺮي: ﺑﺮ اﺳﺎس ﻧﺘﺎﯾﺞ ﻣﻮرد ﻣﻄﺎﻟﻌﻪ ﻣﯿﺰان ﮐﺎرﺳﯿﻨﻮم ﮐﯿﺴﻪ ﺻﻔﺮا در زﻧﺎن ﺑﯿﺸﺘﺮ از ﻣﺮدان اﺳﺖ و ﻋﻤﺪﺗﺎً در ﻣﺮاﺣﻞ پيشرفته ﺗﺸﺤﯿﺺ داده ﻣﯽﺷﻮد، ﺑﻨﺎﺑﺮاﯾﻦ ﺑﺮرﺳﯽ ﭘﺎﺗﻮﻟﻮژﯾﮏ ﻫﻤﻪ ﻧﻤﻮﻧﻪﻫﺎي ﮐﻮﻟﻪ ﺳﯿﺴﺘﮑﺘﻮﻣﯽ ﺗﻮﺻﯿﻪ ﻣﯽﺷﻮد.

Introduction & Objective: Cholecystitis is one the most common disease in gastrointestinal tract which can be presented as acute or chronic cholecystitis. Several environmental, pathological and physiological factors cause this disease .On the other hand gall bladder carcinoma 2-4 percent of gastrointestinal tract malignancies included, that prevalence in 1 to 2 percent of patients who have cholecystectomy. The outbreak and epidemiologic features of chilecystitis has changed clue to revolutionized style of living. The purpose of this study was to investigation of prevalence of acute, chronic of this disease and gall bladder carcinoma and relation with envirement and physiological parameter patient who have cholecystitis. Materials & Methods: The patient who operated of cholecystectomy in 1394 in Amiralmomenin Hospital of Zabol with diagnosis of cholecystectomy were selected and assessed. The patient were divided into acute, chronic and gallbladder carcinoma groups based on their surgical and pathological finding and patient information records. The data analyzed by using SPSS. Results: 271 patients in the study were evaluated 199 (73.4%) patients were women and 72 (26.6%) patients were men and also 131 (48.3%) patients were living in the villages while 140 (51.7%) patient were living in the city. 142 (52.4%) patients were chronic cholecystitis and 129 (47.6%) patients were acute cholecystitis and 8 patients were gall bladder carcinoma. Gallbladder carcinoma was higher in women (60%). The highest incidence of the gall bladder carcinoma were between 40-50 years (24.7%). The Prevalence of cholecystitis were significant relationship with sex and age. Conclusions: According to this study age, sex and living place is effective in present of cholecystitis (acute, chronic, gallbladder carcinoma).This could be related to hormonal differences personal activity due to the diversity of urban and rural life. In the most patient of gall bladder carcinoma, carcinoma occurs with manifestation of gall stone. So maybe prophylactic cholecystectomy be useful for chronic gall stone.