شيوع مصرف مت‌آمفتامين در دانش‌آموزان پسر ايراني: مطالعه مرور ساختارمند و متاآناليز

The Prevalence of Methamphetamine Useamong Iranianmale Students: a Systematic Review and Meta-analysis

سوء­مصرف موادمخدر صنعتي همانند مت­آمفتامين يكي از مشكلات مهم رفتاري در دانش­ آموزان و نوجوانان مي­باشد، به­ طوري­كه سازمان جهاني بهداشت از آن به­عنوان رويدادي نگران­كننده در جهان ياد كرده است. بنابراين هدف اين مطالعه بررسي شيوع مصرف مت­آمفتامين در دانش­ آموزان پسر ايراني در قالب يك مطالعه متاآناليز مي­باشد. مطالعه متاآناليز حاضر با استفاده از مدل تصادفي (Random effect model) انجام گرديده است. براي انتخاب مطالعات انجام شده شيوع مصرف مت­آمفتامين در دانش­آموزان ايراني در پايگاه­هاي SID، Iranmedex، Magira، Pubmed، ISI و Scopus بين سال­هاي1380 تا 1394 مورد جستجو قرار گرفتند كه 69 مقاله استخراج گرديد. پس از بررسي مقالات بر اساس معيارهاي ورود 10 مقاله وارد مطالعه حاضر شدند كه با استفاده از نرم افزارCMA-2 مورد تركيب و تجزيه تحليل قرار گرفتند. براي تعيين ناهمگني (Heterogeneity) بين مطالعات از شاخص­هاي Q، 2Ƭ و I2 استفاده شده است.

Background: The use of industrial drug such as methamphetamine ,reported asan important health problemin students and adolescents in around the world. It was regarded as a concerning event in the students by World Health Organization (WHO). Therefore, the aim of present study was determining prevalence of methamphetamine in the Iranian male student using a meta-analysis study. Material and Methods: the present meta-analysis was conducted using random effect model. For the selecting studies on the prevalence of methamphetamine were searched in SID, Iranmedex, Magiran, Medlib, Pubmed, ISIand Scopus databases by three researchers from 2001 to2014. Then, were identified 69articles and after reviewing based on inclusion and exclusion criteria wereincluded10 articles in the study and was used from the random-effects model by CMA-2 software for analyzing data. Also, the heterogeneity was determined to Q,Ƭ2 and I2 coefficients. Results:The pooled effect size (prevalence)was obtained around 1.2% (CI 95%: 0.8-1.6). Also, in the subgroup analysis, the prevalence of amphetamine was attained 1.6% and 0.9%after and before 2010, respectively. Moreover, the indices related to heterogeneity were including; Q=6.38, I2=0.31 and T2=0.16. In addition, there was a significant association between age and the prevalence of methamphetamine (B=1.13, p=0.01) in the meta-regression analysis. Discussion: Although, the prevalence of methamphetamine was less than other drugs in the male students. But, the increasing prevalence of methamphetamine in the Iranian students, especially in male students, is as a serious warning to the authorities and families.