مقايسه سبك زندگي در بيماران مبتلا به سندرم تخمدان پلي‌كيستيك و زنان سالم

Comparing life style of patients with polycystic ovary syndrome and normal women

زمينه و هدف: بيماري يا سندرم تخمدان پلي‌كيستيك بيماري شايع با علت ناشناخته در سن باروري زنان است. اين بيماري از شايع‌ترين اختلالات نورواندوكرين-متابوليكي در سن ياد‌شده مي‌باشد. پژوهش‌هاي دهه‌ي اخير نقش مهم كيفيت زندگي و سبك زندگي را در اين زنان دخيل مي‌داند. هدف اين مطالعه بررسي الگوي خواب و كيفيت زندگي مبتلايان به تخمدان پلي‌كيستيك بود. روش بررسي: اين مطالعه موردي-شاهدي به بررسي سبك زندگي بيماران مبتلا به تخمدان پلي‌كيستيك پرداخته كه از فروردين تا اسفند 1395 به درمانگاه نازايي ولي‌عصر (عج) بيمارستان امام‌خميني (ره) تهران مراجعه نمودند. حجم نمونه در اين بررسي 168 نفر بود كه در دو گروه مطالعه و شاهد با محدوده‌ي سني 20 تا 40 سال و با شاخص توده‌ي بدني كمتر از 28 شركت نمودند. ابعاد سبك زندگي در اين مطالعه با پرسشنامه‌هاي كيفيت زندگي عمومي، كيفيت خواب پيتزبورگ، افسردگي-اضطراب-استرس و پرسشنامه دموگرافيك بررسي شد. يافته‌ها: ميانگين شاخص توده بدني در گروه مطالعه (0/002=P) و همچنين وزن اين بيماران (0/001

Background: Polycystic ovary syndrome (PCOS) is one of the most common neuroendocrine- metabolic disorders at the infertile age. Patients with PCO often at risk for secondary complications including metabolic difficulties (impaired glucose tolerance, insulin resistance, type 2 diabetes mellitus), reproductive (hirsutism, hypeandrogenism, infertility) and psychological features (worsened quality of life, anxiety, depression). Studies of the past decade suggest that the quality of life is important in the improvement of this syndrome. The purpose of this study was to provide an accurate pattern in the lifestyle of these women. Methods: This case-control study was conducted to assess the lifestyle of patients with polycystic ovary syndrome who referred to Vali-e-Asr Infertile Clinic of Imam Khomeini Hospital, Tehran, from March to February 2015. After filling the consent form, 168 women participated in this study with the age range of 20-40 years and the body mass index (BMI) less than 28 m2/kg. The dimensions of lifestyle in this study were evaluated by the following questionnaires: general qualities of life (GHQ-28), Pittsburgh sleep quality, depression-anxiety-stress (DASS-42) and researcher-made demographic questionnaire. Results: The mean of BMI and weight in study group were higher than control group (P= 0.002) (P< 0.001). Symptoms of PCOS such as irregular cycle (P< 0.001) and hirsutism (P< 0.001) in the study group were greater than the control group. Sleep problems such as drug use (P= 0.048), late sleep (P= 0.024), and sleep adequacy (P= 0.049) were also higher in the study group than control group. Conclusion: These results indicate that environmental factors can easily effect on the quality of life in PCO women. The pattern of sleep is not desirable. Menstrual disorder effects on the mood and the impact of the low income generates negative emotions and affects their quality of life, since the cost of treatment for infertility is high for the lowincome families. Therefore, this study indicates that having proper weight and proper sleep can help to plan a correct pattern of lifestyle in these patients.