ميزان شيوع هپاتيت B در بين اهداكنندگان خون مراجعه‌كننده به سازمان انتقال خون: گزارش كوتاه

Prevalence of hepatitis B among blood donors referring to blood transfusion organization: brief report

زمينه و هدف: هپاتيت B از شايعترين عفونت‌هـاي ويروسـي قابـل انتقـال از راه خون است كه همچنان يكي از مشكلات بهداشتي جهان محسوب مي‌شود. هدف از اين مطالعه، بررسي شيوع عفونت ويروس هپاتيت B ميان اهداكنندگان خون بود. روش بررسي: اين مطالعه توصيفي مقطعي گذشته‌نگر، در 216004 نفر اهداكنندگان خون داوطلب مراجعه‌كننده به پايگاه‌هاي انتقال خون از ابتداي فروردين سال 1390 تا 1394 انجام گرديد. سپس آزمايش آنتي‌ژن سطحي هپاتيت B مثبت با روش الايزا (Enzyme-linked immunosorbent assay, ELISA) و نوتراليزاسيون انجام گرفت. يافته‌ها: در افراد مورد مطالعه، 279 نفر آنتي‌ژن سطحي هپاتيت B مثبت بودند كه 97/14% مرد و 2/86% زن بودند كه اين اختلاف از لحاظ آماري معنادار بود (0/001

Background: Hepatitis B is the most common blood-borne viral infection that is considered as a major public health problem of the world's major health problems. The aim of this study was to investigate the prevalence of hepatitis B virus (HBV) infection among blood donors referring to blood transfusion centers. Methods: This retrospective cross-sectional study was performed on 216004 volunteer blood donors referring to blood transfusion centers of Iran from the beginning of April 2011 to April 2015. Then the positive hepatitis B surface antigen (HBsAg) test was performed using the enzyme-linked immunosorbent assay (ELISA) and neutralization methods. Results: Of the 216004 blood donors, 279 (12.12%) were positive for HBsAg, and the incidence of infection was a decreasing trend over a four-year period. Among HbsAg positive cases, 97.14% and 2.86% were male and female, respectively. Significant differences between males and females were found (P=0.000). The number of HBsAg positive cases among married people (238 cases, 85.3%) in compared with single people (41 cases, 14.7%) was significantly higher (P=0.000). The average age of HBV infected cases was 39.6±10.3 years. Most HBsAg positive cases were 45-36 years old (30.8%) and lowest prevalence was seen in the age group above 56 years old (4.6%). Highest infected people with Hepatitis B Virus had low degree of education. Relationships between HBV infection with age and degree of education were statistically significant (P=0.000). Conclusion: The results of this study showed that based on our findings, prevalence of hepatitis B surface antigen among blood donors have declined significantly during the four years of study.