آثار تمرين مقاومتي با شدت‌هاي بالا و متوسط بر پروفايل ليپيدي، شاخص گلايسميك و FGF21 در بيماران ديابتي نوع دو

The Effect of Resistance Training with High and Moderate Intensities on Lipid Profile, Glycemic Index and FGF21 in Type 2 Diabetic Patients

ﭘﮋوﻫﺶ ﺣﺎﺿﺮ ﺑﺎ ﻫﺪف ﺑﺮرﺳﯽ ﺗﺄﺛﯿﺮ 12 ﻫﻔﺘﻪ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﺑﺎ ﺷﺪتﻫﺎي ﺑﺎﻻ و ﻣﺘﻮﺳﻂ ﺑﺮ ﮐﻨﺘﺮل ﻣﺘﺎﺑﻮﻟﯿﮏ ﻣﺮدان دﯾﺎﺑﺘﯽ ﻧﻮع دو اﻧﺠﺎم ﮔﺮﻓﺖ. 32 ﻣﺮد دﯾﺎﺑﺘﯽ ﻧﻮع دو ﺑﺎ ﻣﯿﺎﻧﮕﯿﻦ ﺳﻨﯽ 1/94± 47/98 ﺳﺎل ﺑﻪﺻﻮرت ﺗﺼﺎدﻓﯽ ﺑﻪ ﺳﻪ ﮔﺮوه، ﺷﺪت ﻣﺘﻮﺳﻂ (12 ﻫﻔﺘﻪ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﺑﺎ ﺷﺪت 60 ﺗﺎ 65 درﺻﺪ ﯾﮏ ﺗﮑﺮار ﺑﯿﺸﯿﻨﻪ در 3 ﺳﺖ ﺑﺎ 12 ﺗﮑﺮار)، ﺷﺪت ﺑﺎﻻ (12 ﻫﻔﺘﻪ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﺑﺎ ﺷﺪت80 ﺗﺎ 85 درﺻﺪ ﯾﮏ ﺗﮑـﺮار ﺑﯿﺸﯿﻨﻪ در4 ﺳﺖ ﺑﺎ 7 ﺗﮑﺮار) و ﮐﻨﺘﺮل (ﺑﺪون ﻫﯿﭻ ﺑﺮﻧﺎﻣﮥ ﺗﻤﺮﯾﻨﯽ) ﺗﻘﺴﯿﻢ ﺷـﺪﻧﺪ. ﻧﻤﻮﻧﮥ ﺧﻮﻧﯽ ﭘﺲ از10 ﺳﺎﻋﺖ ﻧﺎﺷﺘﺎﯾﯽ ﺷﺒﺎﻧﻪ، ﻗﺒﻞ و ﭘﺲ از اﺗﻤﺎم ﺑﺮﻧﺎﻣﮥ ﺗﻤﺮﯾﻨﯽ اﺧﺬ ﺷﺪ. آﻧﺎﻟﯿﺰ وارﯾﺎﻧﺲ ﺑﺎ اﻧﺪازهﮔﯿﺮي ﻣﮑﺮر (ﺑﺎ ﺗﻌﺎﻣﻞ درونﮔﺮوﻫﯽ ﺑﯿﻦﮔﺮوﻫﯽ) ﺑﻪﻣﻨﻈﻮر ﺗﺤﻠﯿﻞ دادهﻫﺎ اﺳﺘﻔﺎده ﺷﺪ. ﻣﻘﺎوﻣﺖ ﺑﻪ اﻧﺴﻮﻟﯿﻦ، ﺗﺮي ﮔﻠﯿﺴﺮﯾﺪ و ﺷﺎﺧﺺ ﺗﻮدة ﺑﺪﻧﯽ ﺗﻐﯿﯿﺮ ﻣﻌﻨﺎداري ﻧﺪاﺷﺘﻨﺪ. ﻫﻤﻮﮔﻠﻮﺑﯿﻦ ﮔﻠﯿﮑﻮزﯾﻠﻪ، LDL،HDL ، درﺻﺪ ﭼﺮﺑﯽ و ﻗﺪرت ﻋﻀﻼﻧﯽ در ﮔﺮوهﻫﺎي ﺗﺠﺮﺑﯽ، ﻧﺴﺒﺖ ﺑﻪ ﮔﺮوه ﮐﻨﺘﺮل ﺑﻬﺒﻮد ﻣﻌﻨﺎداري ﯾﺎﻓﺘﻨﺪ. ﻓﺎﮐﺘﻮر رﺷﺪ ﻓﯿﺒﺮوﺑﻼﺳﺘﯽ 21 در ﻫﺮ دو ﮔﺮوه ﺗﺠﺮﺑﯽ در ﭘﺲآزﻣﻮن اﻓﺰاﯾﺸﯽ ﻣﻌﻨﺎدار داﺷﺖ ﮐﻪ اﯾﻦ اﻓﺰاﯾﺶ ﻧﺴﺒﺖ ﺑﻪ ﮔﺮوه ﮐﻨﺘﺮل ﻧﯿﺰ ﻣﻌﻨﺎدار ﺑﻮد. در ﻣﺠﻤﻮع ﻣﯽﺗﻮان ﮔﻔﺖ ﺗﻤﺮﯾﻨﺎت ﻣﻘﺎوﻣﺘﯽ و ﺑﻪوﯾﮋه ﺗﻤﺮﯾﻨﺎت ﺑﺎ ﺷﺪت ﺑﺎﻻﺗﺮ، در ﺑﻬﺒﻮد ﭘﺮوﻓﺎﯾﻞ ﮔﻼﯾﺴﻤﯿﮏ و ﻟﯿﭙﯿﺪي در اﻓﺮاد ﻣﺒﺘﻼ ﺑﻪ دﯾﺎﺑﺖ ﻧﻮع دو ﻧﻘﺶ ﻣﺆﺛﺮي دارد.

This study aimed at evaluating the effect of 12 weeks of resistance training with high and moderate intensities on metabolic control in type 2 diabetic men.32 men with type 2 diabetes (mean age of 47.98±1.94 years) were randomly divided into three groups: moderate intensity (12 weeks of resistance training with 60-65% of one repetition maximum, 3 sets with 12 repetitions), high intensity (12 weeks of resistance training with 80-85% of one repetition maximum, 4 sets with 7 repetitions) and the control (no training).Blood samples were collected before and after the training program after 10 hours of overnight fasting. The ANOVA with repeated measures (within-group and between-group interactions) was used for data analysis. Insulin resistance, triglyceride and BMI did not change significantly.Glycated hemoglobin, LDL, HDL, body fat percent and muscular strength significantly improved in the experimental groups in comparison with the control group. FGF21 significantly increased in both experimental groups in the posttest and this increase was significant in comparison with the control group.Overall, it can be stated that resistance training, particularly resistance training with higher intensity, has a significant role in improving glycemic and lipid profiles in patients with type 2 diabetes.