بررسي رابطه بين ويتامين D سرم و پوسيدگي دندان بر اساس شاخص ICDAS در دانشجويان دندانپزشكي دانشگاه علوم پزشكي تهران

Evaluating the associations between serum vitamin D levels and dental caries (ICDAS index) among dental students of Tehran university of medical sciences

زﻣﯿﻨﻪ و ﻫﺪف: ﭘﻮﺳﯿﺪﮔﯽ دﻧﺪان ﺑﯿﻤﺎري ﺷﺎﯾﻌﯽ اﺳﺖ ﮐﻪ ﻣﻨﺠﺮ ﺑﻪ ﮐﺎﻫﺶ ﮐﯿﻔﯿﺖ زﻧﺪﮔﯽ اﻓﺮاد ﻣﯽﺷﻮد. ﺗﺤﻘﯿﻖ ﺣﺎﺿﺮ ﺑﺎ ﻫﺪف ﺑﺮرﺳﯽ راﺑﻄﻪ ﺑﯿﻦ ﻣﯿﺎﻧﮕﯿﻦ وﯾﺘﺎﻣﯿﻦ D ﺳﺮم و ﭘﻮﺳﯿﺪﮔﯽ دﻧﺪاﻧﯽ در داﻧﺸﺠﻮﯾﺎن دﻧﺪاﻧﭙﺰﺷﮑﯽ داﻧﺸﮕﺎه ﻋﻠﻮم ﭘﺰﺷﮑﯽ ﺗﻬﺮان اﻧﺠﺎم ﺷﺪ. روش ﺑﺮرﺳﯽ: اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﺗﻮﺻﯿﻔﯽ- ﻣﻘﻄﻌﯽ ﺑﺮ روي 123 ﻧﻔﺮ از داﻧﺸﺠﻮﯾﺎن دﻧﺪان ﭘﺰﺷﮑﯽ ﺳﺎل ﺳﻮم ﺗﺎ آﺧﺮ اﻧﺠﺎم ﺷﺪ. اﻃﻼﻋﺎت دﻣﻮﮔﺮاﻓﯿﮏ و ﺳﻼﻣﺖ آنﻫﺎ از ﻃﺮﯾﻖ ﭼﮏ ﻟﯿﺴﺖ ﺗﮑﻤﯿﻞ ﮔﺮدﯾﺪ. ﺳﻄﺢ ﺳﺮﻣﯽ وﯾﺘﺎﻣﯿﻦ D اﻓﺮاد از ﻃﺮﯾﻖ ﻧﻤﻮﻧﻪﮔﯿﺮي ﺧﻮﻧﯽ ﺗﻌﯿﯿﻦ ﺷﺪ. ﺑﺮرﺳﯽ ﭘﻮﺳﯿﺪﮔﯽ ﺗﻮﺳﻂ ﺷﺎﺧﺺ ICDAS )international caries detection and assessment system( در دو ﺳﻄﺢ ﺷﺎﻣﻞ D(1-6)MFT )ﻣﺠﻤﻮع دﻧﺪانﻫﺎي ﭘﻮﺳﯿﺪه، ﭘﺮ ﺷﺪه و از دﺳﺖ رﻓﺘﻪ( و D(3-6)MFT )ﻣﺠﻤﻮع دﻧﺪانﻫﺎي ﺑﺎ ﭘﻮﺳﯿﺪﮔﯽ ﭘﯿﺸﺮﻓﺘﻪ، ﭘﺮ ﺷﺪه و از دﺳﺖ رﻓﺘﻪ( ﮔﺰارش ﺷﺪ. ﺑﺮاي آﻧﺎﻟﯿﺰ دادهﻫﺎ از ﻧﺮم اﻓﺰار آﻣﺎري SPSS )statistical package for social sciences( ﻧﺴﺨﻪ 25/0 و آزﻣﻮنﻫﺎي ﻫﻤﺒﺴﺘﮕﯽ و رﮔﺮﺳﯿﻮن اﺳﺘﻔﺎده ﺷﺪ. ﯾﺎﻓﺘﻪﻫﺎ: ﺿﺮﯾﺐ ﻫﻤﺒﺴﺘﮕﯽ ﺑﯿﻦ ﺳﻄﺢ ﺳﺮﻣﯽ وﯾﺘﺎﻣﯿﻦ D و ﺷﺎﺧﺺ ﭘﻮﺳﯿﺪﮔﯽ D(1-6)MFT ﺑﺮاﺑﺮ 0/089- ﺑﺎ P-Value ﻣﻌﺎدل 0/328 ﺑﻮد ﮐﻪ از ﻧﻈﺮ آﻣﺎري ﻣﻌﻨﯽدار ﻧﺒﻮد. آزﻣﻮن رﮔﺮﺳﯿﻮن ﺑﻪ روش backward ﻧﺸﺎن داد ﻣﺘﻐﯿﺮ D(3-6)MFT ﺑﺎ ﻣﺘﻐﯿﺮﻫﺎي ﻣﺴﺘﻘﻞ ﺷﺎﻣﻞ ﮐﻤﺒﻮد وﯾﺘﺎﻣﯿﻦ P<0/001) D(، وزن )0/012=P(، وﯾﺰﯾﺖ ﺳﺎﻟﯿﺎﻧﻪ دﻧﺪان ﭘﺰﺷﮑﯽ )0/023=P( و ﺗﻌﺪاد ﻣﯿﺎن وﻋﺪه ﺷﯿﺮﯾﻦ در روز )0/03=P( راﺑﻄﻪ آﻣﺎري ﻣﻌﻨﯽدار و ﻣﺴﺘﻘﯿﻢ و ﺑﺎ ﻣﺼﺮف ﺷﯿﺮ در ﻫﻔﺘﻪ )0/026=P( راﺑﻄﻪ آﻣﺎري ﻣﻌﻨﯽدار و ﻋﮑﺲ داﺷﺖ. ﻧﺘﯿﺠﻪﮔﯿﺮي: در داﻧﺸﺠﻮﯾﺎن دﻧﺪاﻧﭙﺰﺷﮑﯽ، اﮔﺮﭼﻪ راﺑﻄﻪاي ﺑﯿﻦ ﮐﻤﺒﻮد وﯾﺘﺎﻣﯿﻦ D ﺳﺮم و ﻣﺮاﺣﻞ اوﻟﯿﻪ ﭘﻮﺳﯿﺪﮔﯽ دﻧﺪان ﺑﻪ دﺳﺖ ﻧﯿﺎﻣﺪ، اﻣﺎ اﯾﻦ راﺑﻄﻪ در ﻣﺮاﺣﻞ ﭘﯿﺸﺮﻓﺖ ﭘﻮﺳﯿﺪﮔﯽ دﯾﺪه ﺷﺪ.

Dental caries is a multifactorial and common disease that leads to a decrease in the quality of life of individuals. The aim of this study was to determine the relationship between serum vitamin D and dental caries in the third year-to-last year students of dental school of Tehran University of Medical Sciences. Materials and Methods This descriptive cross-sectional study was conducted on 123 dental students. Demographic and health information were completed through a checklist. The level of vitamin D in individuals was measured by blood sampling. We recorded caries by ICDAS (international caries detection and assessment system) in two levels of D(1-6)MFT (total of decayed, filled and missing tooth) and D(3-6)MFT (total of progressive decayed, filled and missing tooth). Data analysis was done by the SPSS package version 25 using statistical tests of correlation and regression. Results The results showed that the correlation coefficient between vitamin D and caries index D(1-6)MFT was -0.89 with a P-value of 0.3328 which was not statistically significant. Based on the backward logistic regression, there was a positive significant statistical association between the D(3-6)MFT with vitamin D deficiency (P<0.001), weight (P=0.012), dental visit (P=0.023) and frequency of sweet snack consumption (P=0.03). In addition a significant and inverse statistical association was reported between the D(3-6)MFT and milk consumption (P=0.026). Conclusion Among dentistry students, no relation between vitamin D deficiency and early stages of decay was seen, however this relation was statistically significant in regard with progressive dental caries.