عنوان مقاله :
مدلبندي طرح هاي متقاطع 2 ضربدر 2 با حضور اثر منتقله براي داده هاي دوتايي
عنوان به زبان ديگر :
Modelling 2x2 cross-over designs with carry-over effect for binary responses
پديد آورندگان :
جهاني هاشمي ، حسن نويسنده دانشگاه علوم پزشكي قزوين Hashemi, H
كليدواژه :
پزشكي , اثر منتقله , cross-over desings , Longitudinal studies , Generalized Liner Models (GLM) , Carry-over effect , Transition (Markov) model , Correlated responses , Wash-out period , Logit , داده هاي دوتايي , طرح هاي متقاطع
چكيده لاتين :
In Parallel designs which each patient receives only one treatment we need a large number of patients for assessing treatment effects. Cross-over trials are Known as longitudinal studies. In cross-over trials each patient is his or her own control and hence it is possible to make more precise result, that is, small number of patients is sufficient In modelling cross-over designs two important issues must be considered: (i) carry-over effect (ii) correlated responses for each patient. In this paper, by using generalized linear models (GLM), we present a transition (Markov) model for binary responses which enables us take into account two important issues simultaneously.
كلمات كليدي :
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