برري بروز اسكار كليه و رابطه ريفلاكس ادراري با آن در كودكان مبتلا به عفونت كليوي

Kidney scar and its relation to the urinary reflux in children suffering from kidney infection

Background: With respect to the high prevalence of UTI and its established risk in kidney scar formation and also the importance of urinary reflux. the present study was conducted on infected children referring to Taleghani and Labafinezhad hospitals in 1997-98. Materials and methods: Thirty six kidneys were studied. Kidney infection was diagnosed based on clinical manifestation, positive urine culture. and abnormal scan using T,99DSMA. Children with urinary system anomalies or previous scar formation were excluded. Reflux was detected by VCUG (standard VCUG in boys and isotopic VCUG in girls). Patients were followed up for at least 6 months. Finally, scar formation and the role of urinary reflux were determined. Results: Of 36 kidneys, 5 (13.2%) revealed scar formation. We have considered I 1 kidneys without reflux as the control group and 25 kidneys with reflux as the case group, among which, 9.1% of the control group and 16% of the case group developed scar. The difference was not statistically significant. Meanwhile, scar formation was more frequent in younger children. Conclusion: Since scar formation is strongly correlated with UTI and hypertension and end stage renal disease are late complications of kidney scar, prevention, early diagnosis, optimal treatment and follow up arc highly recommended in children suffering from UTI.