بررسي نتايج درماني فسفر پرتوزا در تومورهاي كيتيك مغزي در بيمارستان شهداء تجريش در سالهاي 80-1377

Background: The use of interstitial radiotherapy to treat brain tumors is well documented. The survival rate of the brain tumor and better outcome in patients treated with interstitial radiotherapy suggests a difference by authors, thus, we have conducted a retrospective study on patients referring to Shohada Tajrish Hospital during a 3-year period, 1998-2001. Materials and methods: Patientʹs age, sex, operation approach, location and grading of tumor, field of vision, visual acuity, and hormonal changes were all recorded. Results: The study population included 6 males and 6 females developed cystic brain tumor with the mean age of 12.75 years. Of these, I O had craniopharyngioma and 2 had cystic astrocytoma. Patients underwent stereotaxic surgery and interstitial radiotherapy by radioactive phosphorous was performed. No mortality was reported during or after the procedure. Patients were followed up for 28.8 months (4 months- 4 years). During long term follow up visual acuity progressed in 5 patients, remained unchanged in 4 and worsened in 3. Neuroimaging analysis (CT scan and MRI) revealed 10 lesions to be smaller but 2 were enlarged due to the solid part. Conclusion: We have found desirable results in patients with cystic brain tumor who undergone interstitial radiotherapy by radioactive phosphorous. We suggest this technique in affected individuals.