چكيده لاتين :
Background: Osteoarthritis of knee is one of the most common joint disease in human. Hyaline-therapy is its latest treatment approach. We have compared the effects of hyaline-therapy and NSAIDs in patients referring to Akhtar hospital and private clinics in Tehran and Gorgan during a 2-year period, 1999-2001.
Materials and methods: Individuals were assigned in two groups: control group (45) using NSAID with/or without arthrosynthesis and case group (23) using hyaline-therapy (3 injections in10 days).Groups were matched according to the sex, age, and severity of pain. Severity of pain was assessed using ASRA classification. Patients were followed up 3 and 6 months later.
Results: Hyaline-therapy was comparable with NSAID and arthrosynthesis in class I and II . In class III, 75% of patients treated with Synovisc got better and were transferred to lower classes ( I or II). Simultaneous usage of NSAID and arthrosynthesis was successful to cure 33% of patients. Conclusion: Hyaline-therapy revealed to be effective inpatients with severe knee osteoarthritis. Further studeis are highly recommended.
