پديد آورندگان :
Ghavidel, Farideh Department of Medical Laboratory Sciences - Varastegan Institute for Medical Science - Mashhad, Iran , Keyfi, Fatemeh Department of Medical Laboratory Sciences - Varastegan Institute for Medical Science - Mashhad, Iran , Vosoughi, Mahdieh Department of Medical Laboratory Sciences - Varastegan Institute for Medical Science - Mashhad, Iran , Derafsheh, Aref Department of Medical Laboratory Sciences - Varastegan Institute for Medical Science - Mashhad, Iran , Mokhtariye, Armin Department of Medical Laboratory Sciences - Varastegan Institute for Medical Science - Mashhad, Iran , Pouresmaeil, Omid Department of Medical Laboratory Sciences - Varastegan Institute for Medical Science - Mashhad, Iran , Marzban, Sima Pardis Clinical and Genetic Laboratory, Mashhad, Iran , Baledi, Fatemeh Department of Medical Laboratory Sciences - Varastegan Institute for Medical Science - Mashhad, Iran
كليدواژه :
Hyperthyroidism , Hypothyroidism , Gastric inflammation , H. pylori
چكيده لاتين :
Background:
Hyperthyroidism and hypothyroidism are common thyroid disorders. Thyroid hormones have a great role in regulating mucosal cells
and the growth of the gastrointestinal tract. In this study, we investigated the presence of Helicobacter pylori (H. pylori) infection in
various types of thyroid disorders.
Materials and Methods:
Our study included 297 patients whose thyroid status was identified by evaluation of thyroid hormones; triiodothyronine (T3),
thyroxine (T4), and thyroid-stimulating hormone (TSH) using Roche Electrochemiluminescence (ECL). H. pylori antibodies
and antigen were evaluated by enzyme-linked immunosorbent assay (ELISA) kits in all cases.
Results:
Hypothyroidism had a significant correlation with H. pylori infection (p < 0.001). Hyperthyroidism was not related to H. pylori infection
(p = 0.171). Also, in hypothyroidism, female sex more than male sex had a significant correlation with H. pylori infection (p = 0.004).
Conclusion:
Decreasing thyroid hormones can result in dysregulation of gastric mucosal cells, therefore hypothyroidism can lead to more
chance of having H. pylori infection.
