تحليل ويژگي هاي باليني و پيامد بيماري در بيماران مشكوك و قطعي كوويد-19 (ساوه 1399)

Clinical Features and Outcomes of Suspected and Confirmed COVID-19 Patients in Saveh, Iran, 2020

شيوع كرونا ويروس يك تهديد بزرگ براي سلامت جهاني است، چرا كه بسيار مسري است و به سرعت به روش انتقال انسان به انسان گسترش مي يابد. اين مطالعه با هدف ارزيابي ويژگي هاي باليني و پيامد، در بيماران مشكوك و قطعي كوويد-19 ساوه، انجام پذيرفت. مواد و روش ها اين مطالعه توصيفي- تحليلي، بر روي 1463 بيمار مشكوك و قطعي كوويد-19 كه از 28 بهمن 98 لغايت 13 خرداد 1399 به مراكز درماني ساوه مراجعه كرده بودند، انجام گرفت. براي جمع آوري داده ها از پرسشنامه محقق ساخته، شامل اطلاعات دموگرافيك، اپيدميولوژيك و نيز پرونده پزشكي بيماران استفاده شد. يافته ها: ﯾﺎﻓﺘﻪﻫﺎ: در ﺑﯿﻤﺎران ﮐﺮوﻧﺎ ﻣﺜﺒﺖ و ﻣﻨﻔﯽ از ﻧﻈﺮ ﺟﻨﺲ، ﺳﻦ، ﻣﺪت ﺑﺴﺘﺮي در ﺑﯿﻤﺎرﺳﺘﺎن و ﺗﻤﺎس ﺑﺎ ﮐﻮوﯾـﺪ-19 اﺧـﺘﻼف ﻣﻌﻨﯽ داري وﺟﻮد داﺷﺖ )P<0/05(. ﻋﻼﺋﻢ اﺻﻠﯽ ﺑﯿﻤـﺎران ﮐﻮوﯾـﺪ 19 ﺷـﺎﻣﻞ ﺳـﺮﻓﻪ )43/8 درﺻـﺪ(، ﺗـﺐ )41/4 درﺻـﺪ(، و ﺗﻨﮕﯽ ﻧﻔﺲ )40/3 درﺻﺪ( ﺑﻮد. ﻣﻬﻢﺗﺮﯾﻦ ﺑﯿﻤﺎريﻫﺎي زﻣﯿﻨﻪ اي ﺑﯿﻤﺎران ﮐﻮوﯾﺪ 19، ﺷﺎﻣﻞ ﺑﯿﻤﺎري ﻫﺎي ﻗﻠﺒﯽ ﻋﺮوﻗﯽ، دﯾﺎﺑـﺖ و ﻓﺸﺎر ﺧﻮن ﺑﻪ ﺗﺮﺗﯿﺐ ﺑﺎ 11/5 ،12/9 و 7/7 درﺻﺪ ﺑﻮد. ﻣﯿﺎﻧﮕﯿﻦ ﺳﻨﯽ ﺑﯿﻤﺎران ﻓﻮت ﺷﺪه 70/2±15/6 و ﻣـﺮدان )66/2 درﺻـﺪ( ميزان مرگ و مير بالاتري داشتند. استنتاج براي كنترل گسترش عفونت و كاهش مرگ و مير و عوارض ناشي از آن بايد از كمپين ها و مداخلات بيش تري براي بهبود دانش و رفتار عموم مردم به ويژه گروه هاي آسيب پذير همچون سالمندان و افراد داراي بيماري هاي زمينه اي در مورد نحوه انتقال بيماري، استفاده شود.

The outbreak of Coronavirus Disease 2019 (COVID-19) pneumonia is a major threat to global public health because it is very contagious and spreads quickly by human-tohuman transmission. This study aimed to investigate the clinical characteristics and outcome of patients infected with COVID-19 in Saveh, Iran. Materials and methods: A descriptive-analytical study was conducted in 1537 patients with suspected or confirmed COVID-19 from 18 February- 2 June 2020. Medical records were studied and a researcher-made questionnaire consisting of demographic information, epidemiological, and clinical manifestations were used to collect the data. Results: There were significant differences between patients tested positive and negative for COVID-19 in terms of gender, age, duration of hospitalization, and contact with a patient with confirmed COVID-19 (P<0.05). The main symptoms of patients included cough (43.8%), fever (41.4%), and dyspnea (40.3%). The most common chronic diseases in these patients were cardiovascular disease (12.9%), diabetes (11.5%), and hypertension (9.7%). The mean age of death due to COVID-19 was 70.2±15.6 years and higher rate of mortality was seen in men (66.2%). Conclusion: While responding to COVID-19, health authorities should consider vulnerable groups (older patients and those with underlying diseases) and provide them with more information on the modes of transmission of COVID-19 and the risks of infection.