واﺑﺴﺘﮕﯽ ﺑﻪ ﻣﻮاد ﻣﺨﺪر ﺑﺎ اﺧﺘﻼل در ﻋﻤﻠﮑﺮد اﻧﺪامﻫﺎي ﻣﺨﺘﻠﻒ ﺑﺪن، ﺑﻮﯾﮋه رﯾﻪﻫﺎ ﻫﻤﺮاه اﺳﺖ. ﻫﺪف از اﯾﻦ ﺗﺤﻘﯿﻖ ﺗﻌﯿﯿﻦ اﺛﺮ ﺗﻤﺮﯾﻦ ورزﺷﯽ زﯾﺮ ﺑﯿﺸﯿﻨﻪ ﻫﻮازي ﺑﺮ ﻋﻤﻠﮑﺮد رﯾﻮي اﻓﺮاد واﺑﺴﺘﻪ ﺑﻪ ﻣﻮاد ﻣﺨﺪر ﺑﻮد.
ﺗﺤﻘﯿﻖ ﺣﺎﺿﺮ از ﻧﻮع ﺗﺤﻘﯿﻘﺎت ﻧﯿﻤﻪ ﺗﺠﺮﺑﯽ ﺑﺎ ﻃﺮح دو وﻫﻠﻪ ﭘﯿﺶ آزﻣﻮن و ﭘﺲ آزﻣﻮن ﺑﻮد. ﻧﻤﻮﻧﻪ آﻣﺎري ﺗﺤﻘﯿﻖ را 20 ﻓﺮد 33-20 ﺳﺎﻟﻪ واﺑﺴﺘﻪ ﺑﻪ ﻣﻮاد ﻣﺨﺪر ﺗﺸﮑﯿﻞ ﻣﯽدادﻧﺪ ﮐﻪ در ﮔﺮوهﻫﺎي ﺗﺠﺮﺑﯽ ﺗﻤﺮﯾﻦ– دارو درﻣﺎﻧﯽ )10 ﻓﺮد( و دارو درﻣﺎﻧﯽ )10 ﻓﺮد( ﻗﺮار ﮔﺮﻓﺘﻨﺪ. ﮔﺮوه اول ﻣﺘﺸﮑﻞ از اﻓﺮادي ﺑﻮدﻧﺪ ﮐﻪ ﻋﻼوه ﺑﺮ ﻣﺼﺮف روزاﻧﻪ 10 ﻣﯿﻠﯽﮔﺮم ﻣﺘﺎدون، ﻓﻌﺎﻟﯿﺖ ورزﺷﯽ را ﺑﺎ ﺷﺪﺗﯽ ﺑﺮاﺑﺮ 70 اﻟﯽ 75 درﺻﺪ VO2max ﺑﻪ ﻣﺪت 20 ﺟﻠﺴﻪ ﻣﺘﺪاوم ﺗﻤﺮﯾﻨﯽ اﻧﺠﺎم ﻣﯽدادﻧﺪ. در ﻣﻘﺎﺑﻞ ﮔﺮوه دوم ﻣﺘﺸﮑﻞ از اﻓﺮادي ﺑﻮدﻧﺪ ﮐﻪ ﺗﻨﻬﺎ روزاﻧﻪ 10 ﻣﯿﻠﯽﮔﺮم ﻣﺘﺎدون ﻣﺼﺮف ﻣﯽﮐﺮدﻧﺪ. ﭘﺲ از ﭘﺎﯾﺎن ﻣﺪاﺧﻠﻪﻫﺎي ﺗﺤﻘﯿﻖ، ﺷﺎﺧﺺﻫﺎي ﻋﻤﻠﮑﺮد رﯾﻮي ﺑﺮرﺳﯽ ﺷﺪﻧﺪ. در ﻧﻬﺎﯾﺖ، دادهﻫﺎ ﺑﺎ اﺳﺘﻔﺎده از ﻧﺮم اﻓﺰار آﻣﺎري Stata ﻣﻮرد ﺗﺠﺰﯾﻪ و ﺗﺤﻠﯿﻞ ﻗﺮار ﮔﺮﻓﺖ.
ﺗﺠﺰﯾﻪ و ﺗﺤﻠﯿﻞ آﻣﺎري ﺑﯿﺎﻧﮕﺮ اﻓﺰاﯾﺶ ﻣﻌﻨﺎدار آزﻣﻮنﻫﺎي ﻋﻤﻠﮑﺮد رﯾﻮي ﻧﻈﯿﺮFEF25 ،PEF ،FEV1 ،FEV1/FVC ، FEF50 ،FEF25-75 و FEF75 ﺗﻨﻬﺎ در ﮔﺮوه ﺗﻤﺮﯾﻦ– دارو درﻣﺎﻧﯽ ﺑﻮد )0/05
چكيده لاتين :
There is an association between opioid addiction and dysfunction of various body organs, especially lungs. This study was aimed to determine the effect of sub-maximal aerobic training on pulmonary function tests in addicts.
As a quasi–experimental with pre- and post-test designed study, 20 addicted male (20-33 years old) participated in. The participants were divided into exercise-drug supplement (n=10) and drug supplement (n=10) groups. In first group, the subjects consumed 10 milligrams Methadone daily and performed exercise training with 70-75 percent of VO2max as a sub-maximal intensity for twenty sessions. In second group, the participants only consumed 10 milligrams Methadone daily. By the end of study interventions, the pulmonary function indices in subjects were assessed. Finally, data analysis was performed by Stata software.
The statistical analysis showed that the pulmonary function tests such as FEV1/FVC, FEV1, PEF, FEF25, FEF25-75, FEF50 and FEF75 were significantly increased in exercise-drug supplement group (p<0.05). In addition, the rate of FEV1/FVC were significantly increased in drug supplement group (p<0.05). Moreover, serum levels of CC16 were significantly decreased in exercise-drug supplement group (P=0.029, t9=2.591).
The study results showed that in comparison to only drug supplement, the drug plus exercise supplement is more appropriate for the improvement of pulmonary function in addict subjects. However, further researches are need to confirm the results.