LONG با پروتكل IVF/ICSI در بيماران نابارور كانديد OCP نتايج درماني متعاقب مصرف

A study on infertile women undergoing IVF/ICSI by Long protocol and OCP

The effects of oral contraceptive treatment, on pregnancy rate were studied through a randomized clinical trial on 20-35 years old infertile women undergoing IVF/ICSI with Long protocol in Valie-Asre Hospital, Reproductive-health Research Center. One hundred and twenty eligible patients randomly assigned into two groups after getting informed consent. The patients in control group were treated with GnRh agonist initiated in the 21th day of menstrual cycle. Then they received HMG from the 3rd day of next cycle, based on sufficient criteria of pituitary suppression. The case group were given OCP(LD) I daily which started on 5th through 21th day of menstrual cycle. The GnRh agonist were begun on 21 th day and treatment were continued the same as the control group. Two groups were similar. regarding age, type and duration of infertility. No significant difference was seen between the control and case groups regarding to the mean of HMG ampules. The mean days of receiving GnRh agonist in the cases was significantly lower than controls (20.1± 3.9 days versus 22.2+4.3 days, P=0.006). The frequency rate of ovarian cysts and hyperstimulation syndrome was similar in both groups. The pregnancy rate per cycle was 18.3% in the intervention cases and 16.7% in controls without any significant differences. There were no significant differences in abortion and full term pregnancy rates between these two groups.