تاثير مصرف گياه ريحان بر غلظت ليپيدهاي خون در افراد مبتلا به ديابت غيروابسته به انسولين

Effects of basil (Ocimum basilicum) intake on blood lipids levels in NlDDM patients

The main purpose of this study was to determine the effects of Ocimum basilicum (OB) expenditure on blood lipids levels in NIDDM patients. In this clinical crossover trial, 16 patients with NIDDM, who were referred to the Research Center for Diabetes in Yazd, were studied, for ten weeks. None of these patients were using hypoglycemic drugs. An estimation of the amount of energy, carbohydrate (CHO), protein(Pro), ,fat, and fiber intakes was done using 3- days food record questionnaire and data analysed by Food Processor II software. Also, before and after each period, the levels of serum cholesterol, triglyceride, LDL and HDL were measured after 8 hours fasting. The patients during two different periods of 4 weeks, with an interval of 14 days between each periods, were consuming either their own regular dietes or OB (in the form of dry powder, 20 gram daily) with their own regular diets. Results indicated that, the mean values of CHO and fiber consumed during the second regimen were significantly more than the first regimen (242.9+47.1 vs. 204.8+48.4, P<0.01 and 20.915.6 vs. 9.6+8.5, P<0.001). The mean fasting total serum cholesterol level at the end of the period using OB with regular diet decreased significantly when compared with the basic values and also with the regular diets (181.1118.4 vs. 199.5126.9, P<0.001 and 181.1+18.4 vs. 196.2+32.7, P<0.05). The mean fasting total serum triglyceride and HDL level at the end of period using OB with regular diet did not change significantly when compared with the basic values and also with the regular diets. The mean fasting serum LDL level at the end of the period using OB with regular diet decreased significantly compared with the basic values and also with the regular diets (102.9118.6 vs. 120.1124.1, P<0.001 and 102.9118.6 vs. 117.5+24.5, P<0.05). These findings indicate that using Ocimum basilicum with one ʹs regular diet has medical benefits in metabolic control of NIDDM patients.