مقاومت ميكروبي نسبت به آنتي بيوتيك هاي رايج مصرفي در بيماران مبتلا به آبسه هاي پوست و بافت هم بند

Antimicrobial resistance of isolates of cutaneous, soft tissue and visceral abscesses

Introduction: Exact diagnosis of bacterial agents in soft tissue abscesses is an important value in antibiotic therapy. This study was performed on 110 patients with soft tissue abscesses to evaluate the causative agents and their antibiotic response, in vitro. Methods: Sampeles were collected.from 110 patients with skin and soft tissue abscesses which were refired to clinical laboratories in Kerman city and then the samples were cultured by routine microbiological methods for isolation of microbial agents. The antibiogram disc agar diffusion technique was used to evaluate the sensitivity of microbial agents to antibiotics. Results: The aerobic microbial agents of soft tissue abscesses included Staphylococcus aureus (51.8%), /3-hemolytic Streptococcus spp (12.7%), Pseudomonas spp (10%), Klebsiella (8.2%), coagulase-negative Staphylococci (6.4%), Escherichia call (6.4%), Enterohacter (4.5%).The highest rate of bacterial sensitivity belonged to ciprofloxacin (95N. After that, erythromycin (79.6%) and ,gentamicin (61.4%) were the most efficacious antibiotics for aerobic microbial treatment in soft tissue abscesses, respectively. The highest rate of microbial resistance belonged to penicillin G (78.3%) and amoxicillin (65.4%), respectively. Conclusion: This study showes that Staphylococcus aureus is the most common etiologic agent in soft tissue abscesses, and regarding the emergence of microbial resistant to current antibiotic therapy, it is recommended that culture and antibiogram must be performed to choose appropriate antibiotics.