بررسي ارزش سيتولوژي لاواژ برونكو آلويولار در تشخيص سرطان ريه

A STUDY OF THE DIAGNOSTIC VALUE OF BRONCHOALVEOLAR LAUAGE CYTOLOGY IN LUNG CANCER

Bronchoalveolar lavage cytology findings place at our disposal valuable diagnostic information a bout various lung diseases . One of the most important uses is the diagnosis of lung cancers which is made possible by bronchial lavage or broncho- alveolar lavage . In various studies concluded in different countries . the diagnostic accuracy of this test has been reported to be 60-75%. To determine the diagnostic value of this procedure , files of 140 suspected lung cancer patients who had undergone hronchoscopy and lavage between the years 1375-1379 (1996-2000) were included in this retrospective study . From among, these patients , 49 cases were confirmed lung cancer by results of tissue biopsy taken during bronchoscope or incisional biopsy . These positive biopsy findings were considered as gold standard , and the bronchoalveolar lavage cytology findings were compared with them . From among th,.ʹ 49 reported cas:;s of cancer , 34 (69%) were men ,and 15(31",0) were women . 25(41%) had squamous cell carcinoma , 15(31%) had adenoearcinoma 0(12%) had small cell carcinoma, and 2 rases (4%) each had the following : bronehoalveoiar carcinoma , large cell cancer , undifferentiated cancer and metastatic cancer, The result, of cytology were positive for carcinoma in 30(61%) the patients , the cytological finding result, without taking into consideration the type of earn r (histopathology) were as follows: sensitivity 66% , specificity 100% , positive predicivie value 100% neg.pred. value 82% and accuracy 86% . The highest percentage of sensitivity shown by the cytological results was for squamous cell carcinoma (66%) and the last sensitivity was for small cell carcinomas (50%). The highest specificity was for small cytology with 60% . Bronchioalveolar lavage otology with 66% sensitivity and 100% specificity can be used for diagnosis of lung cancers.