اثر بتامتازون در پيشگيري از درد، تهوع و استفراغ بعداز عمل

USE OF BETAMETHASONE IN PREVENTION OF POST OPERATIVE PAIN, NAUSEA AND VOMITING

Post operative pain, nausea and vomiting are common and important complications which lead to numerous dangerous effects on multiple organs , thus prevention of these complications are vital and essential. To determine the effect of betamethasone on post operative pain, nausea and vomiting. In this prospective analytical study, 60 patients scheduled for elective surgery were divided in two groups. Under similar conditions of general anesthesia , one group received 12 mg betamethasone (3m1) and the other group received 3ml normal saline intramuscularly before the operation. Patients were followed for pain , nausea and vomiting for 6 hours after the end of the operation and the data was analyzed statistically using t .test . During 4-6 hours after operation 53% , in betamethasone group and 23% in normal saline group did not have pain. Also 93% of patients in betamethasone group and 50% of patients in normal saline group did not have nausea. Vomiting did not occur in any patient from either group. There is a significant statistical difference between , the two groups regarding prevention of post operative pain and nausea (P = 0.00) but there is no significant statistical differenece between the two groups regarding prevention of post operative vomiting.(P=l ). Injection of intramuscular betamethasone preoperatively can decrease incidence of post operative pain and nausea but does not have any effect on post operative vomiting.