بررسي رابطه كهير و يا آنژيوادم مزمن با تيروييديت اتوايميون

ASSOCIATION OF CHRONIC URTICARIA AND / OR ANGIOEDEMA WITH THYROID A UTOIMMUNITY

Introduction: Auto - immune disorders have been implicated as a cause for chronic uricaria and/ or angioedema and thyroid autoimmunity has been increasingly introduced to be associated with that. This study explores the association of thyroid autoimmunity with chronic urticaria and i or angioedema in lsfahani patients. Methods: Anti - thyroperoxidase (Ani - TPO) and anti - thyroglobulin (Anti -- Tg) antibodies. T4 and TSH were detected in 57 patients with chronic urticaria and 1 or angioedema and were compared with that of normal subjects without chronic urticaria or other autoimmune diseases. Results: Anti - TPO and Anti - Tg antibodies had been increased in 26 (45.6%) and 28 (49%) of patients in case group, as compared to 8 (13.2%) and 10 (16.7%) of subjects in control group, respectively. In total. raised titers of thyroid autoantibodies were found in 34 (60%) and 12 (20%) of subjects in case and control groups, respectively. Conclusion: Considering the high prevalence of thyroid autoantibodies in patients with chronic urticaria and / or angioedema, these antibodies should be detected in affected patients, specially in young and middle-aged women.