) S91( و بروسلا آبورتوس )REV1( بررسي اثر ضدميكروبي عصاره كلروفرمي سير (آليسين ) بر روي بروسلا ملي تنسيس

Antimicrobial Effect of Choloroformic Extract of Garlic (Allicin) on Brucella melitensis (Revl) & Brucella abortus (S19)

History and Aims: Brucellosis is a common disease between animal and human. Side effects of brucellosis treatment regime need to finding new antimicrobial agents. Garlic has many compositions such as allicin. Allicin is the most important compound of garlic with antimicrobial activity. Material and Methods: In this study choloroformic extract of garlic was prepared and quantity of allicin calculated. MIC and MBC for two strains, B.melitensis Revi and B.abortus S19 calculated with bc- macrodilution and agar diffusion (agar well) methods. Results and Discussions: Results indicated that 1:160 dilution of extract (128 microgram per ml allicin) was MIC and 1:80 (218 microgram per ml allicin) was MBC for each strains Revi and S19.