كليدواژه :
Hydrogel , Hydrolysis , پلي اتيلن گليكول , پلي متاكريليك اسيد , علوم دارويي , 5-amino salysylic acid , هيدروليز , poly ethylene glucol , پزشكي , هيدروژل , 5- آمينوساليسيليك اسيد , poly methacrylic acid
چكيده لاتين :
pH sensitive hydrogel networks comprising a poly (methacrylic acid) backbone and poly ethylene glycol ester of 5-amino salicylic acid were synthesized by associated complex formation, and their aquilibrium swelling properties were chracterized in water and aqueous solutions of ethanol. The release profiles of hydrogels were obtained by hydrolysis in buffered solutions (pH 1.2, 7.2 and 8.5). These hydrogels are known to exhibit swelling transistions in response to formation of hydrogen bonded complexes. The composition of hydrogels and pH value of hydrlysis medium are known two important factors in hydrolysis behavior of polymers.
