در ميزان تهوع و استفراغ بعد از لاپاروسكوپي )N2O( اثر گاز نيتروز اكسايد

The effect of Nitrous oxide gas (N20) on incidence of nausea and vomiting after laparoscopy

This study, that evaluate the probable effect of N2O in increasing the incidence of nausea and vomiting after laparoscopy, sixty patients, class I or II of ASA physical status, undergoing diagnosed laparoscopy, were enrolled, and randomly divided in to two groups, each had 30 patients. After induction of general anesthesia , during the maintenance of anesthesia, N2Owas not administered to group I of patients (control), and in group II (case), patients received N2 O in 50% concentration with O2. There was no significant difference in heart rate and blood pressure changes, oxygen saturation, and the use of any additional analgesic drug , between two groups (P>0.05). The incidence and intensity of nausea and vomiting in group II, was higher than group I (p=0.0001), which it is significant. Duration of stay in the PACU was shorter in the patients of the group II (P<0.001) compared with the group I. With regared to the increased incidence of nausea and vomiting, we conclude that, it is better not to use N20 in general anesthesia for laparoscopic procedures.