تغييرات فشار داخل چشم ناشي از مصرف ساكسينيل كولين و آتراكوريوم قبل و بعد از عمل جراحي با بيهوشي عمومي

Intraocular pressure changes due to Succinyl-Choline and Atracuriom usage before and after operation with general anesthesia

Introduction. Intraocular pressure (IOP) produced by the aqueous humor secretion, choroidal volume changes and tonocity of extraocular muscles. This pressure is 15 mmHg. Many factors such as age, sex and anesthetic drugs affect on IOP. Elevation of IOP during the eye operation restrics the operation and sometimes causes a serious complication of expulsive hemmorhage. In this study, the effects of two muscle relaxants Atracuriom and Succinyll-Choline drugs usually used in general anesthesia on IOP were compared. Materials and Methods. 70 candidates for operation; at the age of 50Y/O or less were selected. They were divided in two groups. The first group received Atracurium and the second ones Succinyl-Choline. IOP was measured three times; before, during and after the operation by Schiotz tonometer. Results. IOP changes in the Atracuriom group from the first to the second stage (P=0.71), the second to the third stage (P= 0.44) and the first to the third stage (P=0.58) were not significant. IOP change in the Succinyl-Choline group from the first to the second stage (P=0.002) and the second to the third stage (P= 0.001) were significant, but from the first to the third stage (P= 0.77) were not. Conclusion. Succinyl-Choline, the depolarizing muscle relaxant, causes more IOP changes in comparison with Atracuriom, the non-depolarizing muscle relaxant, during the operation.