مقايسه دو پروتكل مختلف پروفيلاكسي آنتي بيوتيك از لحاظ مدت زمان در جراحي هاي ارتوپدي

COMPARISON OF TWO DIFFERENT PROPHYLA-CTIC ANTIBIOTIC PROTOCOLS BASED ON DURATION IN ORTHOPEDIC SURGERIES

Background & Aim : Bone infection after internal fixation of closed fractures is still one of the orthopedic complications. With new and modern sterility techniques, the duration of prophylactic antibiotic therapy has been shortened. The purpose of this study is to compa:v the occurrence of infection between 24 hours and 48 hours prophylactic antibiotic protocols in closed fractures. Materials & Methods : In a prospective double blind study, 210 patients with closed fractures and internal fixation took 24 hours or 48 hours prophylactic antibiotic therapy and the results compared between them. Results : There were 2 infection cases. One of them had a superficial infection in a hip nailing surgery that finally treated with a 2 week antibiotic therapy. She was in 24 hours antibiotic therapy protocol. The other one had a deep infection which happened in a both bone fracture of forearm fixation. He was under a 48 hours prophylactic antibiotic regimen. Discussion : The occurrence of infection in this study was 1% . There was not a meaningful difference between 24 hours and 48 hours antibiotic prophylaxis. It can be concluded that in our operating room conditions and sterility techniques, one may use 24 hours antibiotic prophylaxis instead of 48 hours.