عنوان مقاله :
PET فلويوريد پتاسيم به منظور تصويربرداري استخوان به روش [81 F] توليد فرمول بندي ، كنترل كيفي و مطالعات اوليه زيستي راديوداروي
عنوان به زبان ديگر :
Production, formulation, quality control and primary-biological studies of [18F]KF for skeletal PET scanning
پديد آورندگان :
اميررضا جليليان ، مترجم ,
كليدواژه :
biodistribution , پراكنش بافتي , cyclotron , نگاره برداري به روش گسيل پوزيترون , فلويور- 81 , فلويوريد پتاسيم , F-18(18F) , تصويربرداري , Potassium Fluoride , سيلكوترون , Positron emission tomography , پزشكي هسته اي , PET دوربين
چكيده لاتين :
[188F]KF, considered as a reference standard for positron emission tomography of the skeletal system, was produced by the bombardment of enriched water ([1d 0]H20>95%) with high energy protons in NRCAM cyclotron.
After the extraction ofluoride from enriched water as KF, and passing it through microbial filter and fine adjustment of acidity and osmolality, it was converted into an injectable form.
Pre-clinical investigations and biological controls were performed to determine radioisotope distribution in laboratory rats, thus suitable information was gathered for imaging in human. This radiopharmaceutical was proved to be quite safe and of high quality as a result of testing in laboratory rats.
كلمات كليدي :
#تست#آزمون###امتحان
