كندروساركوماي لگن

Chondrosarcoma of Pelvis(Clinical Course in 28 Cases)

Background: Chondrosarcoma is a primary malignant cartilage forming tumor seen more commonly after fourth and fifth decades of life. It is mostly seen in flat bones of pelvis and around shoulder girdle or in femur. Surgical resection with a wide margin is the main modality of treatment as this tumor is not sensitive to chemotherapy or radiotherapy. This paper analyzes the results of treatment and the survival rate in a group of patients with pelvic chondrosarcomas. Materials and Methods: A total of 28 patients (19 males and 9 females) with chondrosarcoma of pelvis having been treated by different surgeons for the past 20 years were staled in a retrospective manner. The mean age was 38.9 and the average follow-up was 27.8 months. Clinical presentation, surgical methods and complications, and survival rates were studied. Harris Hip Scoring was used to evaluate the functional outcomes in those that limb-sparing surgery was chosen and were still alive at follow-up. Results: Pain and palpable mass were the primary symptoms while two cases had pulmonary metastasis at time of presentation. The tumors were secondary to osteochondromas in 5 and primary chondrosarcornas in the rest. Sixteen patients had low grade and 12 high grade tumors. Twenty-one patients were treated by limb sparing methods and 5 had undergone hemipelvectomy while 2 patients had no surgery. Fourteen patients (12 from limb salvage group and 2 from limb ablation group) are still alive among whom are disease free, 10 have metastatic lesions in lungs and 2 have local recurrence in pelvis. The disease free survival is 32% and overall survival is 27% for patients with pelvic chondrosarcoma. The Harris Hip Scoring was 71 in surviving group. Conclusion: Early diagnosis and wide surgical-margin resection in high grade chondrosarcoma improves prognosis, yeilding higher survival and disease-free-interval rates.