بررسي تداخل داروهاي ضدافسردگي در نسخ بيمه بيماران مراجعه كننده به داروخانه هاي شهر انزلي در سال 1379

Evaluation of Anti-depressant Drugs Interactions in Insured Prescriptions in Anzali in 1379

Drug interactions happen when two or more drugs are administered at the same time. It is known by changing therapeutic effect of drug or drug poisoning. In this research drug interactions of anti-depressant drugs in Anzali in 2000 were evaluated. This descriptive study was conducted on 13692 regular, randomly sampled insured prescriptions. Drug interactions were studied based on the ratings of Drug Interaction Factsʹ book. 2,1.9% of prescriptions had at least one anti-depressant drug (61.2% in women and 38.8% in men). Drug interaction was observed in 22.4% of prescriptions and type of interaction from first degree to fifth was 14.86, 33.95, 13.49, 17.98 and 19.72 percent respectively. Psychologists and neurologists (42.1%), other specialists (21.9%) and general physicians (36%) prescribed these prescriptions. The most drug interaction was observed in other specialistsʹ prescriptions. The mean number of drugs were 3.481-1,13 in prescriptions. Excessive prevalence of anti-depressants and drug interactions in these prescriptions emphasize the correct teaching of practical pharmacology.