علل فلج هاي ناشي از هيپوكالمي در بيماران مراجعه كننده به اورژانس اعصاب مركز پزشكي قايم (عج ) مشهد

Etiology of hypokalemic paralysis in patients who admitted in neurology emergency ward of Ghaem medical center

Introduction: Hypokalemicperiodicparalysi is classified in disorders named chanalopathies. Many cases of hypokalemic paralysis are admitted in Ghaem Hospital every year. In this research we decided to study clinical and paraclinical manifestations and also primary and secondary etiologies of these disorders. Material and Methods: During one year study, 20 patients were admitted with Hypokalemic manifestation. Most of them had eaten high carbohydrate diet. 10 cases had history of drug consumption. In 3 cases, their attacks were related to cold exposure. 2 cases had non neurologic symptoms including nausea, vomiting or myalgia. The longest duration of paralysis was around 6-12 hours. Only in one patient, there was a positive history of familial paralysis. In most of the patients the pattern of weakness was as four limb weakness with lower limbs dominancy. In 16 cases, serum potassium (K) was below 3 meq/I. In 6 cases, ABG showed metabolic acidosis. In 5 casrs, thyroid function tests showed hyperthyroidism. There was laxative consumption in one patient and prolonged diarrhea in another one. Conclusion: This study showed that majority of hypokalemic cases have secondary causes and hypokalemic periodic paralysis is a rare cause.