كارسينوم متاپلاستيك پستان (گزارش دو مورد)

Metaplastic Breast Carcinoma:two Cases report and review of the literature

Introduction: Metaplastic carcinoma is a rare form of breast carcinoma that has Carcinomatous and sarcomatous parts. This malignant tumor often manifest as an irregular, rapidly growing mass in breast and diagnosis of this neoplasm may be difficult to distinguish hiostologically from the other spindle cell lesions in the breast. Metaplastic carcinoma have poor prognosis as compared to the other type of breast carcinoma. The purpose of this report is presenting rare cases of metaplastic breast carcinoma as the cause of malignant breast mass and diagnosis of this neoplasm. In this report we describe two cases of metaplastic of breast in 46 and 40 years old females that after clinical and histopathologic survey confirmed by immunohistochemical method and cytokeratin Antibody. Conclusion: According to unusual morphologic appearance of metaplastic carcinoma of breast, this malignant tumor noticed in diftremtial diagnosis of all breast tumor with spindle cell and confirmed by immunohistochemical method.