بررسي مقاومت استافيلوكوكوس اوريوس در برابر وانكومايسين

Staphylococcus aureus resistant against vancomycin

Introduction: In the 1950ʹs vancomycin was introduced as an effective antibiotic for curing infections caused by methicillin resistant Staphylococcus aureus. Three decade after using vancomycin, resistant coagulase negative staphylococcus to this antibiotic was reported. In this study, we evaluate the Staphylococcus aureus resistant to vancomycin. Materials and methods: During this invesitigatin which lasted for 6 months, 50 Staphylococcus aureus samples were taken from burn wards of each of two Imam - Reza and Gaem hospitals, Mashhad. All selected samples were resistant to methicillin and their MIC to vancomycin was determined. Results: Of 50 separated bacteria from Imam-Reza and Gaem hospitals subjects, 4 patients had MIC equal to 12.5 mg/ml. In isolated samples from Gaem hospital, one case has MIC equal to 12.5 mg/ml. Conclusion: With respect to expanding the resistant toward vancomycin, thus it is recommended to inhibit the resistance of this organism in the wards.